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When one model is not enough:Combining epistemic tools in systems biology
modeling reverse engineering network motifs Rheinberger engineering analogies historical epistemology
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2016/6/13
In recent years, the philosophical focus of the modeling literature has shifted from descriptions of general properties of models to an interest in different model functions. It has been argued that t...
Tracing organizing principles:Learning from the history of systems biology
systems biology organizing principles general systems theory design principles mathematical modeling
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2016/6/13
With the emergence of systems biology the notion of organizing principles is being highlighted as a key research aim. Researchers attempt to ‘reverse engineer’ the functional organization of biologica...
Systems Biology and the Integration of Mechanistic Explanation and Mathematical Explanation
Systems biology integration mechanistic explanation mathematical models mechanisms
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2016/6/12
The paper discusses how systems biology is working toward complex accounts that integrate explanation in terms of mechanisms and explanation by mathematical models—which some philosophers have viewed ...