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干旱是限制植物种植分布、生长发育以及作物产量的主要非生物胁迫因素之一。棉花是重要的经济作物,新疆是中国棉花种植的主要地区,占全国棉花种植面积80%以上。干旱胁迫是影响新疆棉花生产重要的非生物胁迫因素。挖掘关键抗旱基因,揭示棉花对干旱胁迫的应答机制,培育耐逆新材料和新品种,不仅具有重要的科学研究价值,也是服务棉花可持续发展的重要保障。NAC转录因子在植物非生物胁迫信号中起着重要的转录调控作用。然而,...
【分析化学学术报告】Mass Spectrometric detection of membrane-bound proteins and their noncovalent interaction partners
A new method for analyzing protein crystals – developed by Cornell researchers and given a funky two-part name – could open up applications for new drug discovery and other areas of biotechnology and ...
MIT researchers are using artificial intelligence to design new proteins that go beyond those found in nature.
One of the major obstacles that those conducting research on carbohydrates are constantly working to overcome is the limited array of tools available to decipher the role of sugars. As a workaround, m...
Chemists reveal how tau proteins form tangles(图)     tau蛋白  缠结  阿尔茨海默氏症       font style='font-size:12px;'> 2023/6/5
One of the hallmarks of Alzheimer’s disease is the presence of neurofibrillary tangles in the brain. These tangles, made of tau proteins, impair neurons’ ability to function normally and can cause the...
Probing how proteins pair up inside cells(图)     蛋白质  配对  癌症  药物治疗       font style='font-size:12px;'> 2023/6/5
Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of ...
Tubby-like蛋白基因(TULPs)以大型多基因家族的形式存在,在环境胁迫中发挥重要作用。然而,关于棉花中TULP家族基因的研究却知之甚少。本研究系统地对4种棉花TULPs的隶属关系、特征及其进化关系进行了鉴定和分析。转录组分析表明GhTULPs参与了环境胁迫和棉花组织发育。同时,我们还预测和分析了TULPs可能的分子调控机制和功能。GhTULP34作为候选基因,在盐胁迫下显著降低转基因拟南...
Within the last decade, scientists have adapted CRISPR systems from microbes into gene editing technology, a precise and programmable system for modifying DNA. Now, scientists at MIT’s McGovern Instit...
Dueling proteins give shape to plants(图)     Dueling proteins  shape  plants       font style='font-size:12px;'> 2020/10/23
In an elegant choreography, plants take cues from their environment and channel them into forms: flowers, roots and branches. In a new paper published in Nature Communications, biologist Doris Wa...
Proteins’ Fluorescence A Little Less Mysterious(图)     Proteins  Fluorescence  Little Less  Mysterious       font style='font-size:12px;'> 2018/2/1
Rice University scientists have effectively quenched a debate over the mechanism behind a fluorescent biosensor that monitors neurons by sensing changes in voltage.The work led by Rice theoretical che...
An artificial system using a DNA-laced hydrogel can receive a chemical signal and release the appropriate protein, according to Penn State researchers. Further stimulation by the chemical signal conti...
新乡学院生命科学技术学院基因工程课件 Expression and Modification of Recombinant Proteins
Hand over hand. That's how new, near-atomic resolution, 3-D snapshots show that a key biological machine unfolds a ribbon of protein through its central channel.The machine is a protein complex called...
Investigating folding stability and dynamics of proteins     folding  stability  dynamics  proteins       font style='font-size:12px;'> 2017/7/24
Hydrogels are polymer materials that can absorb a large amount of water, making them flexible like human tissue. They are used in a number of medical applications, including contact lenses, wound dres...

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