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Connecting Motors and Membranes: A Quantitative Investigation of Dynein Pathway Components and in vitro Characterization of the NUM1 Coiled Coil Domain
Connecting Motors and Membranes Dynein Pathway Components vitro Characterization NUM1 Coiled Coil Domain
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2014/12/12
In the budding yeast, Saccharomyces Cerevisiae, dynein, a minus-end directed motor, is involved in nuclear migration and proper orientation of the mitotic spindle during mitosis. Our lab has developed...
Molecular and genetic characterization of the 10.4 kDa cytoplasmic dynein light chain and its effects on the neuroanatomy of {\it Drosophila\/}
Molecular and genetic tools neural development gene causes axis the cytoplasm protein light chain gene
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2014/12/11
We utilized the powerful molecular and genetic tools available for the analysis of neural development in Drosophila to characterize a mutation for its effects on imaginal sensory axons. Previous analy...
The Activity of eg5 and Dynein During Mammalian Mitosis
Dynein Eg5 Flux Mitosis Spindle Assembly
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2014/12/10
The development and maintenance of multicellular organisms depends fundamentally on cell division, a series of events largely mediated by the mitotic spindle. Errors in spindle formation and/or functi...