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Glycine protects cardiomyocytes against lethal reoxygenation injury by inhibiting mitochondrial permeability transition
reoxygenation permeability transition
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2014/3/31
Post-ischaemic reperfusion may precipitate cardiomyocyte death upon correction of intra-cellular acidosis due in part to mitochondrial permeability transition. We investigated whether
glycine, an ami...
Mitochondrial Permeability Transition Pore
Mitochondrial Permeability Transition Pore
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2014/3/31
In 1976, Hunter and Haworth first characterized the mitochondrial permeability transition in beef heart mitochondria.
In 1987, Martin Crompton et al. implied that the pore is a unique molecular entit...
Preconditioning delays Ca 2+ -induced mitochondrial permeability transition
Preconditioning Calcium (cellular) Mitochondria Apoptosis Necrosis
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2014/3/31
In protocol 1, New Zealand White rabbits underwent either no intervention (sham group) or 10 min of ischemia followed
by 5 min of reperfusion, preceded (PC) or not (C; control) by one episode of 5 mi...