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Organoids shown to speed glycoengineered vaccine development
类器官 糖工程疫苗 加速
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2023/5/17
Testing the efficacy of a vaccine candidate is typically a long process, with the immune response of an animal model taking around two months.
A multi-institution team, led by Matt DeLisa, the Willia...
Scientists identify two new proteins connected to plant development
Scientists two new proteins connected plant development
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2017/7/20
The discovery of two new proteins could lead to better ways to regulate plant structure and the ability to resist crop stresses such as drought, thus improving agriculture productivity, according...
The role of gluten consumption at an early age in celiac disease development: a further analysis of the prospective PreventCD cohort study
celiac disease children gluten HLA European cohort
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2018/11/13
Background: We previously found that the introduction of small quantities of gluten at 4–6 mo of age did not reduce the risk of celiac disease (CD) in a group of high-risk children. However, the consu...
2017应激蛋白在生长，发育和疾病戈登学术会议（The 2017 Gordon Research Conference on Stress Proteins in Growth, Development & Disease）
Stress Proteins Growth Development Disease
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2017/1/18
The cellular proteome is constantly exposed to a wide variety of proteotoxic stress conditions. These include external stresses, such as elevated temperatures and radiation damage as well as physiolog...
ADF/Cofilin Activation Regulates Actin Polymerization and Tension Development in Canine Tracheal Smooth Muscle
dissertations research thesis
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2015/5/22
The contractile activation of airway smooth muscle tissues stimulates actin polymerization and the inhibition of actin polymerization inhibits tension development. Actin depolymerizing factor (ADF) an...
B cell development and immunoglobulin genes in cattle
Cellular immune globulin genes immune system lymphoid tissue immunoglobulin molecules
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2014/12/11
The objective of this dissertation was to study B cell development and the mechanism of immunoglobulin gene diversification in cattle. The bovine immune system differs from that of the mouse and human...
Characterization of yeast U14 snoRNA interactions required for rRNA processing, and development of a novel in vivo rDNA system for dissecting ribosome biogenesis
U14 small nucleoli ribosomal RNA DNA bases yeast elements
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2014/12/11
U14 small nucleolar RNA (snoRNA) is required for processing of 18S ribosomal RNA. It was hypothesized that U14 might base pair with 18S RNA through two highly conserved U14 sequence elements known as ...
Functional analysis of Moe (Epb4.1l5) in zebrafish development and the identification of novel Epb4.1l5 binding proteins
Zebrafish Protein Mammals Red blood cell protein Embryonic development. The texture of retina
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2014/12/11
The zebrafish protein Mosaic eyes (Moe), and the mammalian orthologue Erythrocyte protein band 4.1-like 5 (Epb4.1l5), are FERM (for Protein 4.1, Ezrin, Radixin, Moesin) domain containing proteins that...
Individual Polychlorinated Biphenyl (PCB) Congeners Interact to Disrupt Thyroid Hormone Action During Development
Biological sciences Health and environmental sciences Endocrine disruptors Polychlorinated biphenyls Thyroid hormones
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2014/12/10
Nearly 20% of U.S. children are reported to have neurobehavioral deficits in part linked to environmental exposure to industrial chemicals like polychlorinated biphenyls (PCBs). PCB exposure is associ...
中国科学院上海生命科学研究院受邀在Development杂志上发表综述论文
生命科学 Development杂志 综述论文
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2014/3/6
近日，中国科学院上海生命科学研究院生物化学与细胞生物学研究所研究员王纲受邀在《发育》(Development)杂志上发表题为The Mediator complex: a master coordinator of transcription and cell lineage development 的科研综述，该综述论文由王纲与其博士后尹景雯合作完成，系统总结了中介体复合物（Mediator c...
中国科学院生物化学与细胞生物学研究所王纲研究员受邀在《Development》杂志发表综述论文
生物化学 细胞生物学 王纲 Development
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2014/3/12
近日，中国科学院生物化学与细胞生物学研究所王纲研究员受邀在《Development》（《发育》）杂志上发表题为"The Mediator complex: a master coordinator of transcription and cell lineage development’的科研综述，该综述论文由王纲研究员与其博士后尹景雯合作完成，系统总结了中介体复合物（Mediator comp...