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Studies on the mode of action and the selectivity of insecticides acting on ligand-gated ion channels in the nervous system
Ligand-gated ion channels Rdl GABA receptors glutamate-gated chloride channels neonicotinoids nicotinic acetylcholine receptors non-competitive inhibitors
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2009/6/1
The mode of action and the mechanisms for the selectivity of neurotoxic insecticides were investigated using computational chemistry, molecular biology, homology modeling of the target site and X-ray ...
Mechanisms of action of insecticides on ligand-gated ion channels
ligand-gated ion channels (LGIC) electrophysiology neurotoxic insecticides
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2009/3/5
Ligand-gated ion channels (LGICs) mediate fast synaptic neurotransmission and are important targets for insecticides. Thus, the actions of several insecticides have been explored in electrophysiolog...