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西安交通大学科研人员与哈佛大学合作破解肿瘤细胞能量代谢的“Warburg Effect”之谜（图）
西安交通大学 肿瘤细胞 能量代谢 Warburg Effect
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2020/9/18
西安交大刘健康教授团队和哈佛大学魏文毅教授等团队紧密合作，经过长达6年多的努力，发现了肿瘤细胞增殖中“细胞周期紊乱”与“细胞代谢紊乱”两者偶联的关键调控通路 Skp2-IDH1/2，为阐明肿瘤细胞Warburg Effect的发生机制和靶向能量代谢防治癌症提供了重要科学证据。相关成果以“Skp2 dictates cell cycle-dependent metabolic oscillation...
Student Self-Analysis of Their Nonsterile Preparations and its Effect on Compounding Confidence
compounding confidence potency analysis course structure
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2019/1/7
Objective. To determine if students who self-analyzed their own nonsterile preparations had increased confidence in their compounding skill.
Methods. Self-efficacy surveys were given to P1 and P3 stu...
Effect of an Individualized Post-Examination Instructor Remediation on Pharmacy Student Performance in a Biochemistry Course
Effect Individualized Post-Examination Remediation
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2018/11/22
Objective. To assess the effectiveness of a post-examination, one-on-one instructor remediation process on student performance in a pharmacy biochemistry course by measuring the degree of score improv...
The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials
blood pressure cardiovascular diseases insulin resistance
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2018/11/19
Background: To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-...
Effect of maternal high dosages of folic acid supplements on neurocognitive development in children at 4–5 y of age: the prospective birth cohort Infancia y Medio Ambiente (INMA) study
folic acid supplements folate pregnancy periconception period child neurocognitive development
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2018/11/19
Background: The benefits of the use of folic acid supplements (FASs) during the periconception period to prevent neural tube defects and to ensure normal brain development in offspring are well known....
Protective effect of homovanillyl alcohol on cardiovascular disease and total mortality: virgin olive oil, wine, and catechol-methylathion
cardiovascular homovanillyl alcohol hydroxytyrosol traditional Mediterranean diet virgin olive oil
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2018/11/14
Background: Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Hydroxytyrosol-related foods have been shown to protect against cardiovascular disease (CVD).
Substituting whole grains for refined grains in a 6-wk randomized trial has a modest effect on gut microbiota and immune and inflammatory markers of healthy adults
gut microbiota healthy adults immune inflammation whole grains
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2018/11/13
Background: Observational studies suggest an inverse association between whole-grain (WG) consumption and inflammation. However, evidence from interventional studies is limited, and few studies have i...
Longitudinal association between fasting blood glucose concentrations and first stroke in hypertensive adults in China: effect of folic acid intervention
Chinese folic acid hyperglycemia hypertension stroke
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2018/11/13
Background: Diabetes is a known risk factor for stroke, but data on its prospective association with first stroke are limited. Folic acid supplementation has been shown to protect against first stroke...
Beneficial effect of high energy intake at lunch rather than dinner on weight loss in healthy obese women in a weight-loss program: a randomized clinical trial
dinner insulin resistance lunch obesity weight-loss diet
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2018/12/14
Background: The association between the time of nutrient intake and health has been described in a few studies. To our knowledge, no study has evaluated the relation between high energy intakes at lun...
Beneficial effect of high energy intake at lunch rather than dinner on weight loss in healthy obese women in a weight-loss program: a randomized clinical trial
dinner insulin resistance lunch obesity weight-loss diet
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2018/12/18
Background: The association between the time of nutrient intake and health has been described in a few studies. To our knowledge, no study has evaluated the relation between high energy intakes at lun...
Effect of vitamin D replacement on indexes of insulin resistance in overweight elderly individuals: a randomized controlled trial
HOMA insulin resistance prediabetes IOM RDA high-dose vitamin D
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2018/12/13
Background: It is unclear whether and at what dose vitamin D supplementation affects insulin resistance (IR).
Effect of Semi-Rigid and Soft Ankle Braces on Static and Dynamic Postural Stability in Young Male Adults
Ankle brace static postural balance dynamic postural balance Dynamic Postural Stability Index
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2016/7/7
Ankle braces have been suggested to protect ankle joints from a sprain by restricting inversion and improving proprioception. However, the difference in effects between a semi-rigid brace and a soft b...
Effect of Wearing the Elevation Training Mask on Aerobic Capacity,Lung Function,and Hematological Variables
Altitude training interval training
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2016/7/7
Altitude training and respiratory muscle training (RMT) have been reported to improve performance in elite and well-trained athletes. Several devices (altitude and RMT) have been developed to help ath...
No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial
sugar-sweetened beverages systemic inflammation adipose tissue inflammation fructose intestinal permeability
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2018/12/3
Background: Sugar-sweetened beverage (SSB) consumption and low-grade chronic inflammation are both independently associated with type 2 diabetes and cardiovascular disease. Fructose, a major component...
No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial
sugar-sweetened beverages systemic inflammation adipose tissue inflammation fructose intestinal permeability
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2018/12/13
Background: Sugar-sweetened beverage (SSB) consumption and low-grade chronic inflammation are both independently associated with type 2 diabetes and cardiovascular disease. Fructose, a major component...