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Illness representations and self-management behaviors of African American adolescents with asthma
illness representations self-management African American
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2015/1/19
African American adolescents have inadequate self-management behaviors, particularly during middle adolescence (14-16 years of age). Inaccurate beliefs, degree of asthma impairment (well controlled or...
Association of the Expression of IL-4 and IL-13 Genes,IL-4 and IgE Serum Levels with Allergic Asthma
Asthma Genes IL-4 IL-13 RT-PCR
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2010/4/9
Immune and inflammatory responses mediated by cytokines, play important roles in the
pathophysiology of asthma. These responses are associated with overexpression of Th2 cytokines
such as IL-4 and I...
Association of the Expression of IL-4 and IL-13 Genes,IL-4 and IgE Serum Levels with Allergic Asthma
Asthma Genes IL-4 IL-13 RT-PCR
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2010/4/9
Immune and inflammatory responses mediated by cytokines, play important roles in the
pathophysiology of asthma. These responses are associated with overexpression of Th2 cytokines
such as IL-4 and I...
Sulfidopeptide leukotrienes, but not thromboxane B2 or histamine, are elevated in sputum during exacerbation of asthma
asthma histamine sputum sulfidopeptide leukotrienes thromboxane B2
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2010/11/25
Although sulfidopeptide leukotrienes (sLT) are considered to play an important role in the pathogenesis of asthma, their precise action has not been elucidated in asthmatics during exacerbation. In th...
Early intervention with inhaled steroids in childhood asthma
childhood asthma early intervention inhaled steroid remodeling
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2010/11/22
Early introduction of inhaled steroids as a treatment for childhood asthma is recommended in the guidelines to achieve not only early control of symptoms with an improvement in patients' quality of li...
Signal transducers and activators of transcription 6 (Stat6) variants in childhood and adult asthma
atopy dinucleotide repeat polymorphism interleukin-13 interleukin-4 signal transducers and activators of transcription 6 (Stat6)
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2010/11/22
Background: Signal transducers and activators of transcription 6 (Stat6) is a key transcription factor involved in interleukin (IL)-4 and IL-13-mediated biological responses. Recently, we reported the...
Identifying Predictors of Response to Suplatast Tosilate among Patients with Moderate to Severe Bronchial Asthma Receiving Inhaled Steroid Therapy
antiasthmatic agent basophil bronchial asthma eosinophil response prediction
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2010/11/22
Twenty-two patients were assessed as responders according to our criteria. The percentage of blood eosinophil (%EOS, P = 0.015) and basophil (%BASO, P = 0.019) counts were identified as significant va...
Glucocorticoid Action and Resistance in Asthma
asthma glucocorticoid resistance therapy
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2010/11/19
In the past decade it has become clear that asthmatic patients who are clinically unresponsive, or ”resistant” to glucocorticoid therapy may have T cells which manifest resistance to glucocorticoid in...
Identification and Function of a Novel Candidate Gene for Asthma: ADAM 33
a disintegrin and metalloprotease 33 asthma epithelial mesenchymal tropic unit genetics
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2010/11/19
Asthma is a complex disorder of inflammation and remodelling largely restricted to the conducting airways. It is a disorder where there are major genetics and environmental factors that interact toget...