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探讨miR-431在肺发育形态学中的潜在作用。方法 根据肺发育分期,选择SpragueDawley大鼠孕16 d(E16)、孕19 d(E19)、孕21 d(E21)、生后1 d(P1)、生后3 d(P3)、生后7 d(P7)、生后14 d(P14)及生后10周(P10周)成年大鼠的肺组织作为观察点,利用苏木精-伊红染色(HE)及透射电镜方法进行肺组织形态学观察;利用荧光原位杂交和实时荧光定量PC...
Development and comparison of a minimallyinvasive model of autologous clot pulmonary embolism in Sprague-Dawley and Copenhagen rats
pulmonary embolism rats pulmonary hypertension
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2014/11/28
Background Experimental models of pulmonary embolism (PE) that produce pulmonary hypertension (PH) employ many different methods of inducing acute pulmonary occlusion. Many of these models induce PE w...