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Stimulation of the proliferation and differentiation of Leydig cell precursors after the destruction of existing Leydig cells with ethane dimethyl sulphonate（EDS）can take place in the absence of LH
proliferation differentiation Leydig cell precursors
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2009/2/23
In hypophysectomized rats, 2 days after the administration of the cytotoxic drug ethane dimethyl sulphonate (EDS), the proliferative activity of Leydig cell precursors increased six-fold. Thus, fact...
The regulation of the proliferation and differentiation of rat Leydig cell precursor cells after EDS administration or daily HCG treatment
Leydig cell Leydig cell precursor LH hCG EDS proliferation
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2009/2/23
The proliferation and differentiation of possible Leydig cell precursors in adult rats were studied after destruction of the existing Leydig cells with EDS or after daily treatment with hCG. After 2...
In vitro differentiation of rat seminiferous tubular segments from defined stages of the epithelial cycle morphologic and immunolocalization analysis
rat seminiferous tubular segments defined stages epithelial cycle morphologic immunolocalization analysis
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2009/2/23
Rat seminiferous tubule segments have been cultured in chemically defined medium (F12/DMEM 1:1) without added hormones or growth factors. The segments (1-2 mm) were isolated from defined stages of t...
Flow cytometric DNA analysis of defined stages of rat seminiferous epithelial cycle during in vitro differentiation
Flow cytometric DNA analysis rat seminiferous epithelial cycle
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2009/2/23
The stages of the rat seminiferous epithelial cycle have been isolated for flow cytometric analysis of DNA and for culture, using transillumination-assisted microdissection. Precise stages have been...
Vitamin E deficiency causes incomplete spermatogenesis and affects the structural differentiation of epithelial cells of the epididymis in the rat
Vitamin E structural differentiation epithelial cells epididymis rat
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2009/2/17
The effects of vitamin E deficiency on the rat testis and epididymis were examined in a light- and electron-microscopic analysis. Various groups of animals were made vitamin E-deficient, beginning...
Hst7：a male sterility mutation perturbing sperm motility, flagellar assembly, and mitochondrial sheath differentiation
Allele asthenospermia axoneme t complex t haplotype
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2009/2/17
Hst7, a mouse hybrid sterility locus, has been mapped in close linkage to four other hybrid sterility loci, on proximal chromosome 17 within the t complex. When an allele (s) of Hst7 from the specie...
Pituitary control of proliferation and differentiation of Leydig cells and their putative precursors in immature hypophysectomized rat testis
Testis rat development Leydig cells steroidogenesis
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2009/2/17
The objective of this study was to determine the effects of pituitary hormones (luteinizing hormone [LH], follicle-stimulating hormone [FSH], growth hormone [GH], and prolactin [PRL]) on interstit...
The distribution of connexin 43 is associated with the germ cell differentiation and with the modulation of the Sertoli cell junctional barrier in continual（guinea pig）and seasonal breeders'（mink）testes
Gap junction Cx43 Sertoli cell blood-testis barrier
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2009/2/13
To test whether the gap junction protein connexin 43 (Cx43) is associated with germ cell differentiation and with the Sertoli cell junctional blood barrier, we recorded the temporal changes in its d...
Growth factors（EGF, IGF-I）modulate the morphological differentiation of adult marmoset(Callithrix jacchus)Sertoli cells in vitro
Marmoset Sertoli cells growth factors in vitro ultrastructure
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2009/2/12
The effects of epidermal growth factor (EGF) and insulin-like growth factor I (IGF-I) on mature marmoset (Callithrix jacchus) Sertoli cells in vitro were investigated using light and electron micr...
Epididymal growth and differentiation are altered in human cryptorchidism
Epididymal growth differentiation human cryptorchidism
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2008/12/26
Despite the knowledge and histological classification of testicular lesions, epididymal lesions associated with cryptorchidism are not well defined and only macroscopic alterations have been reporte...
Mechanism of protection of rat spermatogenesis by hormonal pretreatment：stimulation of spermatogonial differentiation after irradiation
Mechanism protection rat spermatogenesis hormonal pretreatment stimulation irradiation
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2008/12/25
Pretreatment of rats with hormones that suppress testosterone levels and sperm production enhances the recovery of spermatogenesis from stem cells after a cytotoxic insult. It is not known whether t...