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Prolactin-induced Modulation of Tissue Growth Rate Patterns in Albino Rats During Puberal Transition
prolactin growth rate curves tissue somatic indices advancement of puberty accessory male reproductive glands
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2009/2/19
The role of prolactin (PRL) in the puberal transition of male albino rats has been investigated. It was found that PRL elevated total organ growth rates, tissue somatic indices, and dry weights of r...
Modulation of insulin-like growth factor-1 in the seminal plasma of infertile men
Modulation insulin-like growth factor-1 seminal plasma infertile men
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2009/2/18
It has been suggested that insulin-like growth factor (IGF)-1 plays an important role in the regulation of spermatogenesis in the testes. In the present study, concentrations of total IGF-1 we...
Presence and modulation of interleukin-12 in seminal plasma of fertile and infertile men
Cytokines interleukins infertility semen
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2009/2/17
Interleukin-12 (IL-12) is a unique cytokine that recently has drawn considerable attention because of its immunomodulatory properties and its possible involvement in several normal physiological a...
The distribution of connexin 43 is associated with the germ cell differentiation and with the modulation of the Sertoli cell junctional barrier in continual（guinea pig）and seasonal breeders'（mink）testes
Gap junction Cx43 Sertoli cell blood-testis barrier
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2009/2/13
To test whether the gap junction protein connexin 43 (Cx43) is associated with germ cell differentiation and with the Sertoli cell junctional blood barrier, we recorded the temporal changes in its d...
Modulation of androgen receptor transcriptional activity by the estrogen receptor
Androgen receptor estrogen receptor modulation transcription 016 cells GC cells
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2009/2/12
Estrogen/androgen receptor interactions in naturally occurring physiological systems and the effect of their respective steroid hormones on transcriptional activity remain undefined. In an attempt...
Estrogen receptor messenger RNA expression in human benign prostatic hyperplasia：detection, localization, and modulation with a long-acting gonadotropin-releasing hormone agonist
Estrogen receptor messenger RNA expression human benign prostatic hyperplasia detection localization
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2009/2/12
We have analyzed human benign prostatic hyperplastic (BPH) tissue derived from eight radical prostatectomy specimens from patients with prostate cancer for the expression of the estrogen receptor ...
Hormonal modulation of the interactions of cultured rat testicular Sertoli and peritubular myoid cells. Effects on glycosaminoglycan synthesis
Protein sulfoprotein glycosaminoglycan extracellular matrix cocultures
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2009/2/11
Previous investigators have suggested metabolic cooperation between Sertoli and peritubular cells. This study concerns Sertoli cell and peritubular myoid cell interactions in terms of synthesis of...
Modulation of immunoradiometric and bioactive follicle stimulating hormone secretion and clearance in young and elderly men during treatment with tamoxifen or flutamide
pulsatile hormone FSH gonadotropin secretion aging bioactive tamoxifen flutamide
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2009/2/11
The secretion and clearance of immunoactive and bioactive follicle-stimulating hormone (FSH) in healthy young men (N = 10) and elderly men (N = 7) during blockade of endogenous sex steroid hormone...
Receptor Isoform and Ligand-Specific Modulation of Dihydrotestosterone-Induced Prostate Specific Antigen Gene Expression and Prostate Tumor Cell Growth by Estrogens
Androgen receptor androgens estrogen receptor
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2008/12/23
Androgens via the androgen receptor (AR) play crucial roles in prostate physiology and pathophysiology. These androgen actions can be either inhibited or potentiated by estrogens. The mechanisms of ...
Paracrine Modulation of Androgen Synthesis in Rat Leydig Cells by Nitric Oxide
Macrophage testosterone DNA gene array nitric oxide synthase S-nitrosoglutathione L-NG-nitro-arginine methyl ester L-NG-monomethyl-arginine
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2008/12/23
The free radical nitric oxide (NO), generated through the oxidation of L-arginine to L-citrulline by NO synthases (NOSs), has been shown to inhibit steroidogenic pathways. NOS isoforms are known...
Restoration of Erectile Capacity in Normotensive Aged Rats by Modulation of Angiotensin Receptor Type 1
Erectile dysfunction Sprague-Dawley rat losartan
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2008/12/23
We investigated the effects of systemic modulation of angiotensin 2 on the erectile dysfunction of aged rats. Young and aged (18 months old) male Sprague-Dawley rats were either treated with daily a...