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Cholesterol-metabolism study suggests new diagnostic, treatment approach for aggressive prostate cancer（图）
diagnostic prostate cancer
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2014/3/20
WEST LAFAYETTE, Ind. - Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that cou...
Normal gonadal functions and fertility after 23 months of treatment of prepubertal male and female dogs with the GnRh agonist [D-Trp6, des-Gly-NH2(10)]GnRH ethylamide
Normal gonadal functions fertility prepubertal male female dogs
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2009/2/23
The GnRH agonist [D-Trp6, des-Gly-NH2(10)]GnRH ethylamide was administered to prepubertal male and female dogs daily for 23 months by subcutaneous injection. During GnRH agonist treatment, plasma ster...
Mast cells in the testis, epididymis and accessory glands of the rat：effects of neonatal steroid treatment
Mast cells rat neonatal steroid treatment
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2009/2/23
Mast cells in the testis of control adult rats were found almost exclusively around subcapsular blood vessels. Discrete mast cells were distributed throughout the stroma of the epididymis and sex ...
Treatment of men with idiopathic oligozoospermic infertility using the aromatase inhibitor, testolactone. Results of a double-blinded, randomized, placebo-controlled trial with crossover
men idiopathic oligozoospermic infertility aromatase inhibitor testolactone
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2009/2/23
The hypothesis that increased estradiol production may be the cause of impaired spermatogenesis in infertile men with idiopathic oligozoospermia was tested by administering the aromatase inhibitor...
The correlation between the gossypol contents in blood plasma, rete testis fluid, and cauda epididymal fluid following chronic treatment with gossypol in rats
gossypol contents blood plasma rete testis fluid cauda epididymal fluid chronic treatment with gossypol in rats
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2009/2/23
Concentrations of gossypol in blood plasma, rete testis fluid, and fluid from the caudia epididymidis were measured simultaneously by high performance liquid chromatography in rats treated with goss...
The regulation of the proliferation and differentiation of rat Leydig cell precursor cells after EDS administration or daily HCG treatment
Leydig cell Leydig cell precursor LH hCG EDS proliferation
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2009/2/23
The proliferation and differentiation of possible Leydig cell precursors in adult rats were studied after destruction of the existing Leydig cells with EDS or after daily treatment with hCG. After 2...
HCG treatment increases intratesticular pressure in the abdominal testis of unilaterally cryptorchid rats
testis cryptorchidism hCG vascular permeability
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2009/2/23
Adult, unilaterally cryptorchid rats were given a single subcutaneous injection of hCG. HCG treatment of 100 I.U. (but not 10 I.U.) resulted in a marked increase in intratesticular pressure (approxi...
Morphologic changes induced by short-term ischemia in the rat testis are not affected by treatment with superoxide dismutase and catalase
short-term ischemia rat testis superoxide dismutase and catalase
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2009/2/23
Short-term testicular ischemia was induced unilaterally by ligating the testicular artery for 60 or 100 minutes in adult rats. After 7 days, the rats were fixed by vascular perfusion. The effect of ...
Pituitary-testicular function of prostatic cancer patients during treatment with a gonadotropin-releasing hormone agonist analog. II. Endocrinology and histology of the testis
Pituitary-testicular function prostatic cancer patients gonadotropin-releasing hormone
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2009/2/23
Endogenous testosterone (T), LH and FSH receptors, and in vitro production of cyclic adenosine-3':5'-monophosphate (cAMP), T and some of its steroid precursors were measured in testicular tissue obt...
Pituitary-testicular function of prostatic cancer patients during treatment with a gonadotropin-releasing hormone agonist analog. I. Circulating hormone levels
Pituitary-testicular function prostatic cancer patients treatment gonadotropin-releasing hormone
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2009/2/23
Eight patients with advanced prostatic carcinoma (ages 59 to 78 years) were treated with a potent gonadotropin-releasing hormone (GnRH) agonist analog (buserelin, Hoechst; 600 micrograms intranasall...
Variation in the effect of a nongonadotropic Leydig cell stimulating factor in testicular interstitial fluid after exposure of the testis to a single episode of heat treatment
Variation nongonadotropic Leydig cell testicular interstitial fluid testis
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2009/2/23
The activity of a nongonadotropic factor present in rat testicular interstitial fluid and capable of stimulating Leydig cell testosterone production was measured at intervals for 8 weeks after exp...
Testosterone levels after bromocriptine treatment in patients undergoing long-term hemodialysis
impotence bromocriptine hyperprolactinemia
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2009/2/20
Seventeen out of 34 male patients undergoing long-term hemodialysis had increased basal plasma prolactin levels (mean = 1344 +/- 1158.76 mU/L). Seven of these 17 patients having the greatest degre...
Recovery of normal testicular ultrastructure and sperm motility after cessation of gossypol treatment in rats
normal testicular ultrastructure sperm motility gossypol treatment rats
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2009/2/20
This study evaluates the reversibility of the effects of gossypol on testicular ultrastructure and the motility of epididymal spermatozoa. Adult male rats were treated 6 days weekly with the vehic...
Recovery of gonadal functions in the adult male rat following cessation of five-month daily treatment with an LHRH agonist
LHRH agonist testicular steroidogenesis ventral prostate seminal vesicles spermatogenesis
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2009/2/20
This study describes the recovery of various parameters of the pituitary-gonadal axis following five months of daily treatment of adult male rats with a potent LHRH (luteinizing hormone-releasing ...
The effect of exogenous follicle stimulating hormone treatment on anterior pituitary and testicular function in the prepubertal bull
follicle stimulating hormone luteinizing hormone testosterone prepubertal bull
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2009/2/20
The effect of exogenous follicle stimulating hormone (FSH) on testicular function was studied in twenty 4-month-old Holstein bulls during two seasons (ten in late winter and ten in summer). Five mg ...