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研究团队以SARS-CoV-2为实验模型,采用计算机高通量筛选、酶学验证、抗病毒实验和冷冻电镜表征等多学科交叉的方式,从棉花中筛选到一种重要的次生代谢物——棉酚,发现棉酚能够广谱抑制冠状病毒。研究结果开辟了多学科交叉和多元化利用新方向,对促进棉花天然产物的研究和利用、拓宽棉花副产品的价值链具有重要意义。
Infections caused by fungi, such as Candida albicans, pose a significant global health risk due to their resistance to existing treatments, so much so that the World Health Organization has highlighte...
Targeting cancer with a multidrug nanoparticle(图)     瓶刷状颗粒  纳米颗粒  抗癌药物       font style='font-size:12px;'> 2023/6/7
Treating cancer with combinations of drugs can be more effective than using a single drug. However, figuring out the optimal combination of drugs, and making sure that all of the drugs reach the right...
Researchers at MIT’s McGovern Institute for Brain Research have discovered a bacterial enzyme that they say could expand scientists’ CRISPR toolkit, making it easy to cut and edit RNA with the kind of...
近日,中山大学管理学院吴记副教授应邀作题为“Psychological Targeting in Marketing”的线上学术报告。讲座由山大管理学院市场营销系赵海川副教授主持,学院百余师生参与了此次会议。吴记副教授同大家分享了他近期发表在顶级期刊MISQ上的一篇论文,这项研究聚焦于采用大数据和文本挖掘方法识别消费者的调节焦点。吴记副教授指出,人们的心理特征可以从他们的数字足迹中准确地预测出来,...
SARS-CoV-2 is the etiological agent responsible for the global COVID-19 outbreak. The main protease (Mpro) of SARS-CoV-2 is a key enzyme that plays a pivotal role in mediating viral replication and tr...
The recent outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 infection in Wuhan, China has posed a serious threat to global public health. To develop specific anti-coronavirus therapeuti...
Very recently, a novel coronavirus, 2019-nCoV, emerged in Wuhan, China and then quickly spread worldwide, resulting in >17,388 confirmed cases and 361 deaths as of 3 February 2020, thus calling for th...
Concerning the side-channel attacks on Advanced Encryp- tion Standard, it seems that majority of studies focus on the lowest size: AES-128. Even when adaptable to higher sizes (AES-192 and AES-256), l...
By hijacking a cancer cell’s own metabolism, researchers have found a way to tag and target elusive cancers with small-molecule sugars. This opens treatment pathways for cancers that are not responsiv...
This paper presents a study about the potential of spectral unmixing of hyperspectral satellite image data for targeting and quantification of mineral content in limestone and bauxite rich areas in so...
The widespread evolution of multiple herbicide resistance in the most serious annual weeds infesting Australian cropping fields has forced the development of alternative, non-chemical weed cont...
The study of proteins and protein complexes using chemical cross-linking followed by the MS identification of the cross-linked peptides has found increasingly widespread use in recent years. Thus far,...
This paper describes a procedure to measure to high accuracy large and small structures in a static or dynamic state. The process utilizes alternative light to create a specific excitation wave length...
Targeting HIV in Semen to Shut Down AIDS     HIV  Semen  Shut Down AIDS       font style='font-size:12px;'> 2015/9/9
There may be two new ways to fight AIDS -- using a heat shock protein or a small molecule – to attack fibrils in semen associated with the human immunodeficiency virus (HIV) during the initial phases ...

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