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Volta Labs: Improving workflows for genetic applications(图)     基因应用  基因工程  摩尔定律       font style='font-size:12px;'> 2023/6/19
The cost of DNA sequencing has plummeted at a rate faster than Moore’s Law, opening large markets in the sequencing space. Genomics for cancer care alone is predicted to hit $23 billion by 2025, but s...
Researchers at MIT’s McGovern Institute for Brain Research have discovered a bacterial enzyme that they say could expand scientists’ CRISPR toolkit, making it easy to cut and edit RNA with the kind of...
Within the last decade, scientists have adapted CRISPR systems from microbes into gene editing technology, a precise and programmable system for modifying DNA. Now, scientists at MIT’s McGovern Instit...
In recent years, scientists have developed monoclonal antibodies — proteins that mimic the body’s own immune defenses — that can combat a variety of diseases, including some cancers and autoimmune dis...
新技术可识别活体大脑蛋白质(图 )     病毒    大脑  蛋白质       font style='font-size:12px;'> 2021/8/12
研究人员首次开发出可以识别活体动物大脑中蛋白质的新方法,向弄清不同类型神经元中数百万种不同的蛋白质迈出了一大步。2021年8月11日,相关论文发表于《自然—通讯》。该研究有望推动帕金森氏症和阿尔茨海默病等疾病新疗法的开发。
Ateam of researchers led by scientists from Harvard and the Broad Institute used a new gene-editing technique to successfully treat sickle cell disease in mice. This advancement could one day lead to ...
哺乳动物细胞可将RNA序列写入DNA     哺乳动物细胞  RNA  DNA       font style='font-size:12px;'> 2021/6/16
美国费城托马斯杰斐逊大学的研究人员首次发现,哺乳动物细胞可以将RNA序列转换回DNA,这在病毒中比真核细胞更常见。这一发现可能会挑战生物学长期以来的观点,并可能对生物学的众多领域产生广泛影响。相关研究发表在6月11日的《科学进展》杂志上。
Pew scholar builds on gene-editing technology(图)     皮尤学者  基因编辑技术  基因工程       font style='font-size:12px;'> 2023/5/24
Elizabeth Kellogg, assistant professor of molecular biology and genetics in the College of Arts and Sciences, has been named to the Pew Scholars Program to pursue research into advancing gene editing ...
A new technique for correcting disease-causing mutations(图)     致病突变  基因疗法  基因编辑       font style='font-size:12px;'> 2023/6/20
Gene editing, or purposefully changing a gene’s DNA sequence, is a powerful tool for studying how mutations cause disease, and for making changes in an individual’s DNA for therapeutic purposes. A nov...
How metals work together to weaken hardy nitrogen-nitrogen bonds(图)     金属  氮-氮键  氮酶  耐寒       font style='font-size:12px;'> 2023/6/8
Nitrogen, an element that is essential for all living cells, makes up about 78 percent of Earth’s atmosphere. However, most organisms cannot make use of this nitrogen until it is converted into ammoni...
2021年4月14日,COMSATS工业生物技术联合中心成立大会在中国科学院天津工业生物技术研究所举行。会议通过线上线下相结合的方式进行。
《细胞》杂志9日在线发表的一篇论文表示,美国怀特黑德研究所乔纳森·魏斯曼等人设计了一种名为CRISPRoff的新基因编辑技术,可以在不改变DNA序列的情况下使某些基因“沉默”,从而以高特异性控制基因表达。这种“升级版”的基因编辑技术为研究表观遗传机制、重大疾病治疗以及研发新冠病毒疫苗等提供了有力工具。
WOX9:A gene that's a jack of all trades(图)     WOX9  gene that  jack  all trades       font style='font-size:12px;'> 2021/4/9
Over evolutionary time scales, a single gene may acquire different roles in diverging species. However, revealing the multiple hidden roles of a gene was not possible before genome editing came along....
据物理学家组织网23日报道,美国研究人员在最新一期《分子细胞》杂志撰文指出,他们发明了一种新基因编辑技术,可按时间顺序对切割点或编辑点进行编辑,有望促进癌症研究等领域的发展。因编辑领域的“当红炸子鸡”CRISPR使科学家能改变细胞内DNA的序列,或添加所需序列或基因。CRISPR使用名为Cas9的酶,这种酶就像剪刀一样,精确地在DNA内相关位置进行剪切。科学家早在10年前就发现了CRISPR系统的...
The microbial life of sourdough(图)     microbial life  sourdough       font style='font-size:12px;'> 2021/2/5
In a study of 500 sourdough starters on four continents, scientists have gained new insights into how environmental factors contribute to each sourdough starter's microbial ecosystem, and how differen...

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