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Human cells’ protein factory has an alternate operating manual
HIV/AIDS Virus Protein Cell biology Molecular genetics. The ribosome
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2014/7/18
College Park, MD -- Working with a gene that interacts with HIV, University of Maryland researchers have discovered that some human genes have an alternate set of operating instructions written into t...
Scientists discover tool to understand nerve cells（图）
nerve cells cells become damaged
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2014/7/10
A team of international scientists is one step closer to understanding neurodegenerative diseases after developing a tool to explore how nerve cells become damaged.
Analysis of differentiation capacity of Cfp1 null embyronic stem cells
Stem Cells Cell Differentiation Epigenetics DNA Methylation Mice Cardiomyocytes Neurons Leukemia Inhibitory Factor
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2015/5/22
Epigenetics is defined as “the study of stable, often heritable, changes that influence gene expression that are not mediated by DNA sequence” (Fingerman et al., 2013). Epigenetic marks such as covale...
Effects of carbon nanotubes on airway epithelial cells and model lipid bilayers : proteomic and biophysical studies
Carbon Nanotube Calu-3 cells DPhPC lipid bilayer
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2015/5/22
Carbon nanomaterials are widely produced and used in industry, medicine and scientific research. To examine the impact of exposure to nanoparticles on human health, the human airway epithelial cell li...
Role of a putative bacterial lipoprotein in Pseudomonas aeruginosa-mediated cytotoxicity toward airway cells
Pseudomonas aeruginosa infection Cystic Fibrosis Cytotoxicity
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2015/5/22
The patients with Cystic fibrosis (CF), an inherent genetic disorder, suffer from chronic bacterial infection in the lung. In CF, modification of epithelial cells leads to alteration of the lung envir...
Prostaglandin E₂ promotes recovery of hematopoietic stem and progenitor cells after radiation exposure
hematopoiesis radiomitigation radiation
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2015/5/21
The hematopoietic system is highly proliferative, making hematopoietic stem and progenitor cells (HSPC) sensitive to radiation damage. Total body irradiation and chemotherapy, as well as the risk of r...
Rhythmic bursts of electrical activity from cells in ear teach brain how to hea
Rhythmic bursts electrical activity from cells ear teach brain how to hea
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2014/6/19
A precise rhythm of electrical impulses transmitted from cells in the inner ear coaches the brain how to hear, according to a new study led by researchers at the University of Pittsburgh School of Med...
Consequences of telomerase inhibition and telomere dysfunction in BRCA1 mutant cancer cells
telomerase BRCA breast cancer telomeres
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2015/5/21
Telomere maintenance is a critical component of genomic stability. An increasing body of evidence suggests BRCA1, a tumor suppressor gene with a variety of functions including DNA repair and cell cycl...
Direct Interaction between Ras Homolog Enriched in Brain and FK506 Binding Protein 38 in Cashmere Goat Fetal Fibroblast Cells
mammalian Target of Rapamycin [mTOR] Ras homolog enriched in brain [Rheb]
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2016/5/17
Ras homolog enriched in brain (Rheb) and FK506 binding protein 38 (FKBP38) are two important regulatory proteins in the mammalian target of rapamycin (mTOR) pathway. There are contradictory data on th...
Watching HIV bud from cells
HIV bud cells AIDS
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2014/6/12
University of Utah researchers devised a way to watch newly forming AIDS virus particles emerging or “budding” from infected human cells without interfering with the process. The method shows a protei...
Selection of Reference Genes for Gene Expression Studies in Porcine Whole Blood and Peripheral Blood Mononuclear Cells under Polyinosinic:Polycytidylic Acid Stimulation
Peripheral Blood Mononuclear Cells (PBMC) Polyinosinic:Polycytidylic Acid
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2016/5/16
Investigating gene expression of immune cells of whole blood or peripheral blood mononuclear cells (PBMC) under polyinosinic:polycytidylic acid (poly I:C) stimulation is valuable for understanding the...
Effects of Saturated Long-chain Fatty Acid on mRNA Expression of Genes Associated with Milk Fat and Protein Biosynthesis in Bovine Mammary Epithelial Cells
Bovine Mammary Epithelial Cells mRNA Expression Milk Fat Milk Protein
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2016/5/16
This study was conducted to determine the effects of saturated long-chain fatty acids (LCFA) on cell proliferation and triacylglycerol (TAG) content, as well as mRNA expression of αs1-casein (CSN1S1) ...
Siberian Sturgeon Oocyte Extract Induces Epigenetic Modifications of Porcine Somatic Cells and Improves Developmental Competence of SCNT Embryos
Epigenetic Modifications Somatic Cell Nuclear Transfer Siberian Sturgeon Oocyte Extract
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2016/5/16
Somatic cell nuclear transfer (SCNT) has generally demonstrated that a differentiated cell can convert into a undifferentiated or pluripotent state. In the SCNT experiment, nuclear reprogramming is in...
Ovarian cancer cells are more aggressive on soft tissues
Ovarian cancer cells more aggressive soft tissues
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2014/6/12
When ovarian cancer spreads from the ovaries it almost always does so to a layer of fatty tissue that lines the gut. A new study has found that ovarian cancer cells are more aggressive on these soft t...
Secret life of cells revealed with new technique（图）
cells new technique
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2014/7/7
A new technique that allows researchers to conduct experiments more rapidly and accurately is giving insights into the workings of proteins important in heart and muscle diseases.