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Probing how proteins pair up inside cells(图)     蛋白质  配对  癌症  药物治疗       font style='font-size:12px;'> 2023/6/5
Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of ...
New view of lymph nodes shows immune cells in real time(图)     淋巴结  新视图  免疫细胞       font style='font-size:12px;'> 2023/5/23
Cornell researchers have for the first time successfully imaged the entire depth of the lymph nodes in a living mouse using three-photon microscopy. The breakthrough technique’s micrometer clarity and...
In Down syndrome, the third copy of chromosome 21 causes a reorganization of the 3D configuration of the entire genome in a key cell type of the developing brain, a new study shows. The resulting disr...
A protein that causes a cell's skeleton to bend, allowing it to twist the cell into different shapes, could be key to how cells divide according to scientists.
Healthy sleep may rely on long-overlooked brain cells(图)     Healthy sleep  rely on  long-overlooked  jbrain cells       font style='font-size:12px;'> 2021/4/9
For something we spend one-third of our lives doing, we still understand remarkably little about how sleep works -- for example, why can some people sleep deeply through any disturbance, while others ...
脊髓损伤(Spinal Cord Injury, SCI)引起的原发性和继发性白质损伤会导致长期的运动功能缺陷,通过在受损的轴突和目标神经元之间插入新的神经元可以实现功能连接的重建,神经干细胞(Neural Stem Cells, NSCs)有望在脊髓损伤断端之间重建通信。然而,SCI后形成的抑制性微环境往往导致内源性和移植的NSCs向胶质细胞而不是神经元分化。已有研究表明,功能生物材料可减轻SC...
Building on the promise of emerging therapies to deploy the body's "natural killer" immune cells to fight cancer, researchers at the University of Michigan have gone one step farther.They've...
Biochemists have helped answer a fundamental question that has lingered since the discovery of DNA: Is chromatin -- the complex package of DNA and proteins in the nucleus of our cells -- a solid or a ...
New 'molecular computers' find the right cells(图)     molecular computers  right cells       font style='font-size:12px;'> 2020/9/4
Scientists have demonstrated a new way to precisely target cells by distinguishing them from neighboring cells that look similar.Cells that become cancerous may differ from their healthy neighbors in ...
Chromatin organizes into 3D 'forests' in single cells(图)     Chromatin organizes  3D  forests  single cells       font style='font-size:12px;'> 2020/2/20
A single cell contains the genetic instructions for an entire organism. This genomic information is managed and processed by the complex machinery of chromatin -- a mix of DNA and protein in chromosom...
A single drop of seawater can contain a wide representation of ocean microbes from around the world -- revealing new insights into the ecology, evolution and biotechnology potential of the global micr...
Better biosensor technology created for stem cells(图)     biosensor technology  stem cells       font style='font-size:12px;'> 2019/11/15
NSF-funded researchers have created better biosensor technology using a newly developed instrument that may lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other...
In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report finding a potential weak spot in cancer cells that have extra sets of chromosomes, the structur...
Crouching in the boot-sucking mud of the Baylands Nature Preserve in Palo Alto, bioengineer Manu Prakash of Stanford University peered through his Foldscope -- a $1.75 origami microscope of his own in...
Researchers have developed a new technology that allows them to probe cell changes without disturbing the cell's physiology – an advancement that helps scientists look more closely at cell changes to ...

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