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The emission of electrical signals during application of mechanical stress to brittle geo-materials (the so-called pressure-stimulated current; PSC) can provide significant information regarding the m...
In this work, we present a new catalog of focal mechanisms calculated for earthquakes recorded in Sicily and southern Calabria. It comprises about 300 solutions, for events with magnitudes ranging fro...
Shear wave velocity, Vs, is one of the important input parameters in seismic response analysis of the ground. Various methods have been examined to measure the soil Vs directly. Direct measurement of ...
Work described here assessed the feasibility of using variations in tissue thickness in massive Porites corals as a bioindicator for mine-related sediment stress. We examined parameters influencing co...
Previous papers have reported on the performance of a recently developed nonlinear ground response analysis code, SPECTRA, with reference to the prediction of the free-field response at a Large-Scale ...
Phosphorylation of eukaryotic initiation factor 2 (eIF2) is an important mechanism regulating global and gene-specific translation during different environmental stresses. Repressed global translation...
In response to different environmental stresses, phosphorylation of eIF2 (eIF2P) represses global translation coincident with preferential translation of ATF4. ATF4 is a transcriptional activa...
mTORC1 contributes to ER stress induced cell death     LAM  Bortezomib  Rapamycin       font style='font-size:12px;'> 2015/5/25
Patients with the genetic disorder tuberous sclerosis complex (TSC) suffer from neoplastic growths in multiple organ systems. These growths are the result of inactivating mutations in either the TSC1 ...
Neurofibromatosis Type 1 (NF1) is a genetic disorder resulting from mutations in the NF1 tumor suppressor gene. Neurofibromin is the protein product of NF1 and functions as a negative regulator of Ras...
Disruptions of the endoplasmic reticulum (ER) cause perturbations in protein folding and result in a cellular condition known as ER stress. ER stress and the accumulation of unfolded protein activate ...
Bone is a dynamic organ that responds to its external environment. Cell signaling cascades are initiated within bone cells when changes in mechanical loading occur. To describe these molecular signali...
The Lyme disease agent, Borrelia burgdorferi, has a complex system that allows it to thrive in the harsh and distinct environments of its tick vector and mammalian host. Although it has been known for...
Stress adversely affects the wellbeing of commercial chickens, and comes with an economic cost to the industry that cannot be ignored. In this paper, we first develop an inexpensive and non-invasive, ...
UC Berkeley scientists have identified a new molecular pathway critical to aging, and confirmed that the process can be manipulated to help make old blood like new again.The researchers found tha...
. We implement and analyze 13 different metrics (4 moist thermodynamic quantities and 9 heat stress metrics) in the Community Land Model (CLM4.5), the land surface component of the Community Earth ...

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