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Development of Therapies to Treat Polycystic Kidney Disease
Polycystic Kidney Disease Lysophosphatidic Acid PPARγ agonists
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2015/5/22
Polycystic kidney diseases (PKD) are genetic disorders characterized by fluid filled cysts in the kidney tubules and liver bile ducts. There are two forms of PKD, autosomal dominant polycystic kidney ...
ROLE OF GENOMIC COPY NUMBER VARIATION IN ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT
Copy number variation Alzheimer's disease
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2015/5/21
Alzheimer's disease (AD) is the most common form of dementia defined by loss in memory and cognitive abilities severe enough to interfere significantly with daily life activities. Amnestic mild cognit...
Automatic Classification of Early Parkinson’s Disease with Multi-Modal MR Imaging
Automatic Classification Early Parkinson’s Disease Multi-Modal MR Imaging
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2018/4/19
Background: In recent years, neuroimaging has been increasingly used as an objective method for the diagnosis of Parkinson’s disease (PD). Most previous studies were based on invasive imaging modaliti...
Donation to help find a cure for Motor Neuron Disease（图）
Motor Neuron Disease disease
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2014/7/14
The University of Queensland’s Queensland Brain Institute (QBI) has welcomed the support of the MND and Me Foundation in its quest to improve the understanding of Motor Neuron Disease (MND).
Regulation of outer surface lipoprotein A in the Lyme disease spirochete Borrelia burgdorferi
Borrelia burgdorferi OspA
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2015/5/21
Borrelia burgdorferi, a bacterium which causes Lyme disease, is maintained in nature through a cycle involving two distinct hosts: a tick vector and a mammalian host. To adapt to these two diverse env...
Edge-Based Compartmental Modeling for Infectious Disease Spread Part I: An Overview
Infectious Disease Spread
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2011/9/29
The primary tool for predicting infectious disease spread and intervention e ectiveness is the mass action Susceptible-Infected-Recovered model of Kermack and McKendrick . Its usefulness derives large...
Edge-Based Compartmental Modeling for Infectious Disease Spread Part III: Disease and Population Structure
Infectious Disease Part III Disease and Population Structure
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2011/9/29
We consider the edge-based compartmental models for infectious disease spread introduced in .These models allow us to consider standard SIR diseases spreading in random populations. In this paper we s...
An Animal Model of Combined Pituitary Hormone Deficiency Disease
pituitary LHX3 endocrinology knock-in
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2015/5/22
LHX3 is a LIM-homeodomain transcription factor that has essential roles in pituitary and nervous system development in mammals. Children who are homozygous for recessive mutations in the LHX3 gene pre...
A comparison of various influential points diagnostic methods and robust regression approaches: Reanalysis of interstitial lung disease data
robust regression methods local influence likelihood displacement
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2010/9/25
In a linear regression model, the estimation of regression parameters by ordinary least squares method is affected by some anomalous points in the data set. Thus, detection of these abnormal points is...
Effects of Different Dietary Vitamin E Levels on Growth Performance, Non-specific Immune Responses, and Disease Resistance against Vibrio anguillarum in Parrot Fish (Oplegnathus fasciatus)
Vitamin E Requirement Immune Responses Vibrio anguillarum
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2016/5/5
We report nutritional physiology and non-specific immune responses of vitamin E in parrot fish for the first time. This study aimed to investigate the essentiality and requirements in diets based on g...
Killer storms: North Atlantic hurricanes and disease outbreaks in sea urchins
disease outbreaks sea urchins North Atlantic hurricanes
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2014/4/17
An increase in the incidence of disease in various marine organisms over the past few decades has been linked
to ocean climate change. In Nova Scotia, Canada, mass mortalities of sea urchins, due to ...
DNA test to pinpoint risk of disease
DNA test risk of disease
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2010/2/20
A DNA test that reveals a person’s risk of certain diseases could be developed with technology created at the University.Scientists have developed a low-cost method of pinpointing variations in a pers...
Understanding How Disease and Environment Combine to Structure Resistance in Estuarine Bivalve Populations
Delaware bay oyster parasites ecology of infectious diseases oyster population genetics parasite hosts
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2015/7/6
Delaware Bay oyster (Crassostrea virginica) populations are influenced by two lethal parasites that cause Dermo and MSX diseases. As part of the US National Science Foundation Ecology of Infectious Di...
Researcher wins NIH grant to study molecular components of disease
molecular components disease
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2009/10/21
A University of Chicago researcher is among the first to win a new award from the National Institute of Health aimed at supporting research that “has the potential to transform the way we think about ...
Teamwork Tackles Genetic Disease
Teamwork Genetic Disease
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2009/9/16
A pioneering partnership between the University of Greenwich and the University for Modern Science and Arts in Cairo has seen a delegation of Egyptian students working in the laboratories of the Schoo...