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Molecular and functional analysis of mutations that result in insecticide resistance in Colorado potato beetle
Gene mutations pain and the potato beetle biological molecules the rate constant
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2014/12/11
The functional aspects of specific mutations, R30K, S291G, and I392T, found associated with AChE gene of OP- and carbamate-resistant Colorado potato beetle (CPB) were determined using recombinant AChE...
The stability of T7 RNA polymerase elongation complexes and promoter function analysis by in vitro selection
Forward translocation model polymerase complex stability DNA structure
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2014/12/11
The forward translocation model (paused or stalled polymerase moves forward in the absence of transcription, dissociation of the complex happens when hybrid is too short to stabilize the complex) is t...
The building of a centromeric nucleosome: Biochemical analysis and comparison of Cse4p, histone H3 and Cse4-286p to define the unique assembly pathway of a Cse4p nucleosome
Nucleosome chromatin structure octamer core protein chromatin structure cell nuclear cells the cellular mechanisms
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2014/12/11
Nucleosomes are the most fundamental unit of chromatin structure, which is composed of ~～145 bp of DNA wrapped around an octamer of core histones H2A, H2B, H3 and H4. Chromatin structure plays a role ...
Functional analysis of Hic-5/ARA55 isoforms in C2C12 myogenesis
protein protein cell clones hydrogen peroxide androgen receptor activator
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2014/12/11
Hic-5 is a focal adhesion protein of paxillin superfamily that was initially cloned from mouse osteoblasts as a TGF-β or H2O2 inducible cDNA. As well, Hic-5 was independently identified as an Androgen...
Genome-wide analysis for native thyroid hormone targets in developing brain and mechanisms of endocrine disruption at the thyroid hormone receptor
Thyroid hormone fetal brain development interference and signal brain development polychlorinated biphenyls (PCBS)
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2014/12/11
Thyroid hormone (TH) plays an important role in fetal brain development. Therefore, exogenous factors that interfere with TH signaling may exert potentially important adverse effects on brain developm...
Functional analysis of Moe (Epb4.1l5) in zebrafish development and the identification of novel Epb4.1l5 binding proteins
Zebrafish Protein Mammals Red blood cell protein Embryonic development. The texture of retina
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2014/12/11
The zebrafish protein Mosaic eyes (Moe), and the mammalian orthologue Erythrocyte protein band 4.1-like 5 (Epb4.1l5), are FERM (for Protein 4.1, Ezrin, Radixin, Moesin) domain containing proteins that...
Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium
arachidonic acid genome-wide association meta-analysis phospholipid trans fatty acids
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2018/12/20
Background: Circulating trans fatty acids (TFAs), which cannot be synthesized by humans, are linked to adverse health outcomes. Although TFAs are obtained from diet, little is known about subsequent i...
A Hierarchical Spherical Radial Quadrature Algorithm for Multilevel GLMMS, GSMMS, and Gene Pathway Analysis
Generalized Semiparametric Mixed Model multilevel Spherical Radial splines
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2014/12/8
The first part of my thesis is concerned with estimation for longitudinal data using generalized semi-parametric mixed models and multilevel generalized linear mixed models for a binary response. Like...
Modifiable early-life risk factors for childhood adiposity and overweight: an analysis of their combined impact and potential for prevention
adiposity childhood obesity early life obesity lifecourse prevention
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2018/12/20
Background: Early life may be a “critical period” when appetite and regulation of energy balance are programmed, with lifelong consequences for obesity risk. Insight into the potential impact of modif...
Comparative Genome Analysis between Agrostis stolonifera and Members of the Pooideae Subfamily Including Brachypodium distachyon
mapping creeping grass comparative-genome Brachypodium
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2014/11/17
Understanding of grass genome structure and evolution has been significantly advanced through comparative genomics. The genomes of most cool-season forage and turf grasses, belonging to the Pooideae s...
Genetic Variability in Hydrastis Canadensis L. Using RAPD Analysis
genetic variation medicinal plant species goldenseal RAPDs AMOVA UPGMA
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2014/11/17
ABSTRACT GENETIC VARIABILITY IN HYDRASTIS CANADENSIS L. USING RAPD ANALYSIS FEBRUARY 2009 KERRY J. KELLEY, B.A. MOUNT HOLYOKE COLLEGE M.A. UNIVERSITY OF MASSACHUSETTS AMHERST Directed by: Professor Ly...
MU researchers offer first analysis of new human glucose disorder
human glucose disorder MU researchers
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2014/12/1
COLUMBIA, Mo. – Glycogen storage disorders, which affect the body’s ability to process sugar and store energy, are rare metabolic conditions that frequently manifest in the first years of life. Often ...
Microsatellite analysis indicates the specific genetic basis of Czech bolting garlic
Allium sativum L. diversity genotyping SSR markers variety testing
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2014/9/22
Garlic, Allium sativum L., is a vegetable long used for culinary and medical purposes. A certain level of garlic quality is required by the local consumers, which is usually preserved by the varieties...
Green tissue-specific analysis of a cloned rbcS promoter from Lemna gibba
Lemna gibba rbcS SSU5C promoter tissue characterization
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2014/9/22
Many plant genetic engineering taskss require the spatial expression of genes which in turn depends upon the availability of specific promoters. The present paper analyses the green-tissue characteris...
Analysis of integration sites of transgenic sheep generated by lentiviral vectors using next-generation sequencing technology
Gene transfer gene therapy gene transfer the original nucleus
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2015/5/22
The development of new methods to carry out gene transfer has many benefits to several fields, such as gene therapy, agriculture and animal health. The newly established lentiviral vector systems fur...