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A new method for analyzing protein crystals – developed by Cornell researchers and given a funky two-part name – could open up applications for new drug discovery and other areas of biotechnology and ...
MIT researchers are using artificial intelligence to design new proteins that go beyond those found in nature.
One of the major obstacles that those conducting research on carbohydrates are constantly working to overcome is the limited array of tools available to decipher the role of sugars. As a workaround, m...
Chemists reveal how tau proteins form tangles(图)     tau蛋白  缠结  阿尔茨海默氏症       font style='font-size:12px;'> 2023/6/5
One of the hallmarks of Alzheimer’s disease is the presence of neurofibrillary tangles in the brain. These tangles, made of tau proteins, impair neurons’ ability to function normally and can cause the...
Probing how proteins pair up inside cells(图)     蛋白质  配对  癌症  药物治疗       font style='font-size:12px;'> 2023/6/5
Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of ...
Within the last decade, scientists have adapted CRISPR systems from microbes into gene editing technology, a precise and programmable system for modifying DNA. Now, scientists at MIT’s McGovern Instit...
"Combination" Lyme Disease Vaccine Proteins Patented     Lyme disease  bacteria  Vaccine Proteins       font style='font-size:12px;'> 2007/4/10
April 9, 2007,UPTON, NY -- Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators at Stony Brook University have received U.S. Patent Number 7,179,448 for devel...
Googling brain proteins with 3-D goggles(图)     genome  molecules       font style='font-size:12px;'> 2007/3/8
February 15, 2007,RICHLAND, Wash. – The Allen Brain Atlas, a genome-wide map of the mouse brain on the Internet, has been hailed as "Google of the brain." The atlas now has a companion of the brain's ...
Human proteins evolving slowly thanks to multi-tasking genes(图)     proteins  genes       font style='font-size:12px;'> 2007/2/11
06 February 2007,By tweaking these dual role regions, scientists could develop gene therapy techniques that produce proteins that are even better than those found in nature, and could one day be used ...
6 February 2007,Recent investigation of Cullin 4 (CUL4) has ushered this class of multiprotein ubiquitin E3 ligases to center stage as critical regulators of diverse processes including cell cycle reg...
F-box proteins: more than baits for the SCF?     proteins  E3 enzyme       font style='font-size:12px;'> 2006/12/22
13 December 2006,Regulation of protein stability through the ubiquitin proteasome system is a key mechanism underlying numerous cellular processes. The ubiquitin protein ligases (or E3) are in charge ...
Yeast UBL-UBA proteins have partially redundant functions in cell cycle control     Yeast UBL-UBA  proteins       font style='font-size:12px;'> 2006/12/22
4 December 2006,Proteins containing ubiquitin-like (UBL) and ubiquitin associated (UBA) domains have been suggested to shuttle ubiquitinated substrates to the proteasome for degradation. There are thr...
8 December 2006,Fluorescence correlation spectroscopy (FCS) monitors random movements of fluorescent molecules in solution, giving information about the number and the size of for example nano-particl...

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