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Targeted Editing of Myostatin Gene in Sheep by Transcription Activator-like Effector Nucleases
Myostatin Targeted Gene Editing Sheep Primary Fibroblasts
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2016/5/19
Myostatin (MSTN) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Gene knockout of MSTN can result in increasing muscle mass ...
Effects of Castration on Androgen Receptor, IGF-I Ea, MGF and Myostatin Gene Expression in Skeletal Muscles of Male Pigs
Pig Castration Skeletal Muscle Molecular Cloning Gene Expression
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2016/4/29
Castration of male pig produces significant negative effects on skeletal muscle development. The androgen receptor (AR), two splice variants of insulin-like growth factor-I (IGF-I Ea and MGF) and the ...
Effect of Thyroid Hormone on the Gene Expression of Myostatin in Rat Skeletal Muscle
Thyroid Hormone Skeletal Muscle Hyperthyroidism Hypothyroidism Myostatin Expression
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2016/4/29
Modification of thyroid hormone levels has a profound effect on skeletal muscle differentiation, predominantly through direct regulation involving thyroid hormone receptors. Nevertheless, little is kn...
Association of SNP Haplotypes at the Myostatin Gene with Muscular Hypertrophy in Sheep
Double Muscle SSCP Phenotype Haplotype
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2016/4/28
The myostatin gene of seven important meat (Beltex (Australia), BeltexHuyang (F1), Meat and Multi-Prolific Chinese Merino Fine Wool, Meat Chinese Merino Fine Wool and Dorper (South Africa)) an...
Cloning and Prokaryotic Expression of the Mature Fragment of the Chinese Yellow Bovine Myostatin Gene
Prokaryotic Expression Chinese Yellow Bovine Myostatin Gene
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2016/4/25
Myostatin is a member of the transforming growth factor-??(TGF-?? super-family. It acts as a negative regulator for skeletal muscle growth. Myostatin mutations are characterized by a visible, generali...
Suppressed Cell Proliferation and Differentiation Following an Over-expression of Myostatin is Associated with Inhibited Expression of Insulin-like Growth Factor II and Myogenin in Rat L6 Myoblasts
Myostatin IGF Myogenin Myoblast Proliferation Differentiation
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2016/4/22
Myostatin (MSTN) and insulin-like growth factors (IGFs) are a known inhibitor and stimulators of proliferation and differentiation of muscle cells, respectively. The present study was performed to inv...
Effect of Maternal Passive Autoimmunization against Myostatin on Growth Performance in Chickens
Myostatin Autoimmunization Muscle Growth Chicken
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2016/4/19
Myostatin is a negative regulator of skeletal muscle growth and a loss of functional myostatin protein increases muscle hypertrophy and hyperplasia in cattle. The present study was conducted to invest...
Associations of T→A Mutation in the Promoter Region of Myostatin Gene with Birth Weight in Yorkshire Pigs
Pig Myostatin Gene Mutation Birth Weight
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2016/4/12
A T->A mutation in the promoter region of porcine myostatin (MSTN) gene has been identified in our previous work. This study analyzed the associations of the myostatin genotypes (TT, TA) caused by thi...