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Characterization of Insertional Variation of Porcine Endogenous Retroviruses in Six Different Pig Breeds
Insertional Variation Pig Breeds Porcine Endogenous Retroviruses (PERVs) Xenotransplantation
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2016/5/10
Pigs may need to be exploited as xenotransplantation donors due to the shortage of human organs, tissues and cells. Porcine endogenous retroviruses (PERVs) are a significant obstacle to xenotransplant...
Inhibition of Human CD8+ Cytotoxic T Lymphocyte (CTL) -mediated Cytotoxicity in Porcine Fetal Fibroblast Cells by Overexpression of Human Cytomegalovirus Glycoprotein Unique Short (US) 2 Gene
Cytotoxic T Lymphocyte (CTL) cells Swine Leukocyte Antigen (SLA)-I Unique Short (US) 2 Xenotransplantation
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2016/4/28
Xenotransplantation of pig organs into humans is a potential solution for the shortage of donor organs for transplantation. However, multiple immune barriers preclude its clinical application. In part...
Investigation of Deletion Variation and Methylation Patterns in the 5' LTR of Porcine Endogenous Retroviruses
Pigs Long Terminal Repeat (LTR) Porcine Endogenous Retroviruses (PERVs) Xenotransplantation
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2016/4/28
The xenotransplantation of pig organs and cells can be related with a risk of transmission of infectious diseases to human. Previous findings indicate that the regulatory region of PERV for retroviral...
Insertional Variations of Two Porcine Endogenous Retroviruses (PERVs) in Korean Native Pigs and Asian Wild Boars
Pigs Insertional Variations Porcine Endogenous Retroviruses (PERVs) Xenotransplantation
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2016/4/25
Porcine Endogenous Retroviruses (PERVs) are a major concern in relation to xenotransplantation. Previous research indicated that PERVs are present at about 50 copies in the pig genome and their chromo...