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南京农业大学农学院《Nature Communications》发表万建民院士团队“Genome-Wide association studies identify OsWRKY53 as s key regulator of salt tolerance in rice”（图）
万建民 基因 分子机制 蛋白
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2023/10/28
盐碱胁迫影响水稻的生长发育、存活率与最终产量。水稻耐盐碱是由多基因控制的复杂性状。研究水稻应对盐碱胁迫的关键基因及其调控网络，对于培育耐盐碱水稻品种具有重要科学意义和应用价值。2023年6月16日，国际著名期刊Nature Communications发表了万建民院士团队在水稻耐盐碱研究上的新进展。
Association of miR-208b polymorphism with meat quality traits and texture parameters in pigs
miRNAs SNP performance traits Sus scrofa domestica
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2018/11/23
Previous studies have shown that single nucleotide polymorphism (SNP) (rs328743478) located downstream of pre-miR-208b in MYH7 gene is correlated with fibre number composition and drip loss in pigs. B...
L-selectin gene polymorphism and its association with clinical mastitis, somatic cell score, and milk production in Polish Holstein-Friesian cattle
SELL udder inflammation milk production traits cows
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2018/11/23
Bovine mastitis is a widespread disease of the mammary gland, highly contributing to the increase in veterinary costs in dairy industry. In the present study, the genetic polymorphism within bovine L-...
Why might the finding of a new genetic association with inflammatory bowel disease be of potential value in disease control?
new genetic association inflammatory bowel disease potential value disease control
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2018/11/20
Inflammatory bowel disease (IBD) has long been recognized as an exaggerated inflammatory response to common antigenic stimuli in the gut. Ulcerative colitis (UC) (1) and Crohn disease (CD) (2) are the...
Porcine perilipin (PLIN) gene: Structure, polymorphism and association study in Large White pigs
pig perilipin polymorphism
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2015/6/8
Perilipin, encoded by the PLIN gene, is a lipid droplet-associated phosphoprotein that functions as a key regulator of triacylglycerol storage and hydrolysis in adipocytes. In this study, structure an...
FACILITATING PHARMACOGENETIC ASSOCIATION STUDIES USING AN EXTENSIBLE GENOTYPE INFORMATION MANAGEMENT SYSTEM
Large-scale genome Clinical Pharmacology
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2015/5/27
Large-scale genome data projects employing automated, high-throughput techniques have led to a deluge of genomic data that necessitate robust informatic solutions. COBRA-DB is an integrated web-based ...
New international research defends genome-wide association studies
genome-wide genetic variants
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2014/7/17
Since 2005, genome-wide association studies (GWAS) have successfully identified thousands of genes responsible for common human diseases.
A Bayesian Method for Detecting and Characterizing Allelic Heterogeneity and Boosting Signals in Genome-Wide Association Studies
Bayesian Method Detecting Characterizing Allelic Heterogeneity Boosting Signals Genome-Wide Association Studies
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2010/11/16
The standard paradigm for the analysis of genome-wide association studies involves carrying out association tests at both typed and imputed SNPs. These methods will not be optimal for detecting the si...
中国人扩张型心肌病与受磷蛋白基因关系的研究 Association between Mutation of Phospholamban Gene and Dilated Cardiomyopathy
扩张型心肌病 受磷蛋白基因 突变
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2008/1/8
摘要
受磷蛋白（phospholamban）是心肌收缩的一个重要调节因子，可抑制心肌肌浆网钙ATPase的活性、降低其对钙的亲和力。正常情况下，受磷蛋白可被不同的蛋白激酶磷酸化从而解除其肌浆网钙ATPase的抑制作用。国外两个DCM家系研究发现受磷蛋白基因突变与DCM的发生有关，研究目的旨在探讨中国人群心肌特异性受磷蛋白基因突变与特发性扩张型心肌病发病的关系。收集60例确诊的特发性扩张型心肌病...
Association of DNA with nuclear matrix in in vitro assmbled nuclei induced by rDNA from Tetrahymena shanghaiensis in Xenopus egg extracts
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2007/7/28
期刊信息
篇名
Association of DNA with nuclear matrix in in vitro assmbled nuclei induced by rDNA from Tetrahymena shanghaiensis in Xenopus egg extracts
语种
英文
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作者
Chen,Y.,Zhang,B.,et al.,
第一作者单位
北京大学...
Association of differentially expressed gene with activation of mouse hepatic stellate cells by high-density cDNA microarray.
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2007/7/28
期刊信息
篇名
Association of differentially expressed gene with activation of mouse hepatic stellate cells by high-density cDNA microarray.
语种
英文
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作者
5.Xiao-Jing Liu,Li Yang,Feng-Ming Luo,et al
第一作者...