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糖尿病大鼠空回肠PEPT1水平与SP分布的变化
糖尿病 P物质 PEPT1 空回肠
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2012/10/23
研究糖尿病大鼠胃肠排空延迟和空回肠P物质分布的关系，及这一改变是否影响局部寡肽转运体PEPT1的水平。 方法 Wistar大鼠24只，分为3组（n=8）。1型糖尿病模型加胰岛素治疗组，左脲链霉素（streptozocin，STZ）单次股静脉注射（60 mg/kg）诱导1型糖尿病模型，并每天给予1次长效胰岛素（20 U/d，皮下注射）控制血糖。1型糖尿病模型组，左脲链霉素（STZ...
Distribution of the H+/peptide transporter PepT1 in human intestine: up-regulated expression in the colonic mucosa of patients with short-bowel syndrome
PepT1 intestinal mucosa intestinal adaptation peptides transport short-bowel syndrome
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2016/12/17
Background: Intestinal adaptation after massive bowel resection in animal models is characterized by increased gut-mucosal growth and expression of nutrient transporters. Few data about these ind...