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Determining the Latent Tuberculosis Infection by IFN - γ Elispot Assay in Healthcare Workers From University Hospitals of Shiraz, South West of Iran
Latent tuberculosis Tuberculin test Interferon - gamma Enzyme-Linked Immunospot Assay Iran
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2015/9/30
Background: Classical screening methods are incapable to properly detect LTBI (Latent TB Infection) and HCWs (Healthcare Workers) are at the high risk of exposure. Only few reports estimated the preva...
ELISPOT检测HLA-A*0201转基因小鼠对恶性疟原虫红前期候选抗原的CTL应答
疫苗 恶性疟 红细胞前期 细胞毒T淋巴细胞 ELISPOT检测
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2009/2/26
用恶性疟原虫红前期多表位候选抗原PfCP-3tcl（含有1个HLA A*0201限制的CTL表位YLNKIQNSL）免疫人白细胞抗原复合体（HLA）A*0201（HLA-A*0201）转基因小鼠，再用鼠γ干扰素（IFN-γ）酶联免疫吸附斑点法（ELISPOT）检测该转基因小鼠特异性CTL应答，尝试在转基因实验动物中建立评价恶性疟原虫红前期候选抗原CTL应答的方法。结果显示该候选抗原中含有的CTL表...