搜索结果: 1-15 共查到“基础医学 airway”相关记录19条 . 查询时间(0.046 秒)
Expression and Function of the Inducible Costimulator Ligand B7-H2 in Human Airway Smooth Muscle Cells
airway inflammation airway smooth muscle cells B7-H2 DNA synthesis inducible costimulator
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2010/11/16
The data demonstrate that ASM cells express functionally active B7-H2, CD40 and OX40L and suggest that B7-H2-dependent signaling may play an active role in a proliferative response rather than in cyto...
Purified Aged Garlic Extract Modulates Allergic Airway Inflammation in Balb/c Mice
Aged Garlic extract Allergic airway inflammation IFNγ IgG1 IgE Murine model
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2009/12/15
Garlic is known as a potent spice and a medicinal herb with broad therapeutic properties ranging from antibacterial to anticancer and anticoagulant. Our previous studies have shown some immunoregulato...
Chemical Mediators and the Resolution of Airway Inflammation
airway inflammation asthma fish immune response lipid mediators
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2010/11/17
Asthma pathobiology is remarkable for chronic airway inflammation that fails to spontaneously resolve. No curative therapy is currently available. A growing body of evidence indicates that, in health,...
Toll-Like Receptors and Airway Inflammation
airway inflammation bronchial epithelial cells innate immune
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2010/11/17
The respiratory tract opens to the external environment at the oral side edge, and the other edge of the respiratory tract connects to the closed space (alveoli), and so to preserve the sterility in t...
Elimination of IL-13 Reverses Established Goblet Cell Metaplasia into Ciliated Epithelia in Airway Epithelial Cell Culture
anti-IL-13 antibody ciliated cells goblet cells IL-13 transition
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2010/11/19
2 days after elimination of IL-13, the periodic acid-Schiff-positive area as well as MUC5AC protein level rapidly decreased. After 4 days, the number of goblet cells dramatically decreased, while that...
Airway Smooth Muscle and Asthma
airway remodelling airway smooth muscle asthma extracellular matrix inflammation
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2010/11/19
The airway smooth muscle is the key determinant of airway narrowing in asthma but its function in the absence of disease is unknown. Evidence for an intrinsic abnormality in the muscle in asthma is on...
Thromboxane A2 mediates cation-induced airway hyperresponsiveness through the bradykinin B2 receptor in guinea pigs
airway hyperresponsiveness bradykinin cationic protein low molecular weight heparin poly-L-lysine 6-keto-PGF1α thromboxane A2
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2010/11/26
To elucidate the mechanisms of cationic protein-induced airway hyperresponsiveness (AHR), the airway response to methacholine, and the concentrations of thromboxane B2 (TXB2) and 6-keto-PGF1α in the b...
Adrenomedullin stimulates cyclic AMP production in the airway epithelial cells of guinea-pigs and in the human epithelial cell line
adrenomedullin airway cAMP epithelial cell guinea-pig human
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2010/11/26
This study was designed to examine the effects of adrenomedullin (AM) on airway epithelial cells. Primary cultures of guinea-pig tracheal epithelial cells and the human bronchiolar epithelial cell lin...
Effects of formaldehyde, as an indoor air pollutant, on the airway
airway inflammation asthma formaldehyde IgE immune system indoor environments
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2010/11/29
Homes are being built to be more airtight because of demands for energy conservation in recent years. At the same time, recognition of numerous sources of formaldehyde in indoor environments has incre...
Airway responsiveness to acetylcholine or capsaicin in immature and mature guinea pigs in vivo
aging airway obstruction asthma capsaicin neuropeptide
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2010/11/25
Non-specific airway hyperresponsiveness is a characteristic feature of bronchial asthma. Airway reactivity to cholinergics may change with age during childhood. The present paper describes tests to se...
Airway inflammation and repair in asthma
airway remodeling asthma eosinophils inflammation mast cells T cells
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2010/11/25
Asthma is a disease of usually reversible airways obstruction that has prominent inflammation of the mucosa as an underlying feature. It is a disease of varying severity, with some individuals sufferi...
Effect of repeated antigen inhalation on airway inflammation and bronchial responsiveness to acetylcholine in interleukin-5 transgenic mice
bronchial hyperresponsiveness eosinophils interleukin-5 mice
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2010/11/25
Bronchial hyperresponsiveness (BHR) is a characteristic feature of bronchial asthma, yet its precise mechanism remains obscure. Human studies have demonstrated that T helper 2 cytokines, including int...
Mechanical strain-induced DNA synthesis and cell proliferation in human airway smooth muscle cells through extracellular signal-regulated kinase
airway smooth muscle cell extracellular signal-regulated kinase mechanical strain
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2010/11/25
An increased airway muscle content is one of the characteristic features of airway remodeling. Proinflammatory substances, growth factors and mechanical strain promote airway muscle cell proliferation...
Current and potential improvements in the treatment of asthma from increased understanding of airway pathophysiology
β-adrenergic receptor agonists anti-IgE antibody anti-interleukin-5 monoclonal antibody asthma corticosteroids leukotriene inhibitors theophylline
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2010/11/24
The mainstay of chronic asthma management consists of using pharmacological agents that induce broncho-dilatation, such as short-acting β-adrenergic receptor agonists (bronchodilators or relievers), a...
Inhalant corticosteroids inhibit mechanical strain-induced RANTES and eotaxin production by human airway smooth muscle cells
airway smooth muscle cells eotaxin inhaled corticosteroids mechanical strain RANTES
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2010/11/24
The results showed that: (i) mechanical strain, including stretch and compression, stimulated ASM cells to produce RANTES and eotaxin; and (ii) FP and BUD inhibited mechanical strain-induced and TNF-α...