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Background: Basic fibroblast growth factor (bFGF) is a member of a highly conserved superfamily of proteins that are involved in cell proliferation, differentiation, and migration. Objectives: The ob...
Background: B-cell chronic lymphocytic leukemia (B-CLL) is the most common form of leukemia in adults. Some reports showed that expression of ZAP70 gene and chromosomal abnormality are two prognostic ...
Background and the purpose of the study: One of the major concerns about recombinant protein production is its possible toxicity for the organism. Purification of the recombinant protein is another ch...
Background and purpose of the study:Screening of different plant components for new anticancer drugs is one of the main research activities throughout the world. In this study, the anticancer effects ...
Aim: In this preliminary study, we aimed to analyze the effect of sodium butyrate (NB) and phenylbutyrate (PB), belonging to the class of histone deacetylase (HDAC) inhibitors, on lymphoblastoid cell ...
Aim: To investigate annexin A2 (ANXA2), annexin A7 (ANXA7), and annexin A11 (ANXA11) expression in head and neck squamous cell carcinoma (HNSCC). Although overexpression of ANXA2 has been reported in ...
Accumulated eosinophils in the airways in asthma may directly react with HDM and produce IL-9 to further promote Th2-type immune responses. Protease-activated receptor 2, a ligand for serine proteases...
These data indicate that a diversity of tetraspanins is expressed in osteoclast precursors, and that cell fusion during osteoclastogenesis is regulated by cooperation of distinct tetraspanin family pr...
The release of RANTES and MCP-1 was significantly upregulated by histamine compared with the control group. Both carebastine and olopatadine inhibited the release of CC chemokine production to the con...
Background: The present study was undertaken to investigate the correlation of Epidermal Growth Factor Receptor (EGFR) expression with grade of Transitional Cell Carcinoma (TCC). Methods: Tumor sample...
Eosinophil penetration across the basement membrane (BM) is thought to be dependent on the degradation of membrane components. In this process, matrix metalloproteinases (MMP) appear to be primarily r...
Although the clinical effectiveness of long-term low-dose administration of macrolides for diffuse pan- bronchiolitis, sinobronchial syndrome, chronic sinusitis and otitis media with effusion has been...
Analysis of the clinical data confirmed that the proportion of patients who showed greater than 60% improvement in symptoms (47 and 15%) and in rescue medication (79 and 10%) were significant for the ...
Background: Recently, a second prostaglandin D2 (PGD2) receptor, chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), was identified. Because PGD2 was reported to have chemotac...
These results indicate that high expression of Th2-type cytokines concomitant with the infiltration of a predominant number of CD4+ cells and their Th2 subsets play a role in the pathogenesis of eosin...

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