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Gene Expression Profiles of BAD and Bcl-xL in the CA1 Region of the Hippocampus Following Global Ischemic/Reperfusion and FK-506 Administration
Ischemic/Reperfusion Real-Time RT-PCR Hippocampus Tacrolimus Bcl-xL Gene BAD
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2015/12/29
Background: The hippocampus is a tiny nub in the mammalian brain that is involved in forming, organizing, and storing memories. Global cerebral ischemia (GCI) and reperfusion induced apoptosis lead to...
Single-Nucleotide Polymorphisms Within MicroRNAs Sequences and Their 3' UTR Target Sites May Regulate Gene Expression in Gastrointestinal Tract Cancers
MicroRNAs Gastrointestinal Neoplasms Colorectal Neoplasms Gastric Neoplasms
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2015/10/13
Background: Esophageal, stomach, and colorectal cancers are commonly lethal gastrointestinal tract (GIT) neoplasms, causing almost two million deaths worldwide each year. some environmental risk facto...
Expression of Testis Specific Genes TSGA10,TEX101 and ODF3 in Breast Cancer
Testis Gene TSGA10 TEX101 ODF3 Breast Cancer
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2015/9/28
Background: Breast cancer is the most common malignancy in women around the world so finding new biomarkers for early detection and also study on molecular aspects of breast cancer is valuable. Cancer...
Deletion and Testicular Expression of DAZ (Deleted in Azoospermia) Gene in Patients with Non-Obstructive Azoospermia
Infertility Deleted in Azoospermia Gene Y Chromosome Azoospermia Iran
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2009/11/26
Background: Deletions of the DAZ (deleted in azoospermia) genes within the human Y chromosome's AZFc region are the most common cause of spermatogenesis failure. These deletions are usually assessed b...
Effects of the N-Ras Oncogene on the Expression of Other Cellular Genes in CO25 Myoblast Cells
oncogene myoblast ras myc differentiation
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2009/7/3
The effects of the N- ras oncogene on the transcription levels of c- myc, p53, c-K-ras and b-actin genes have been investigated by Northern blotting in a cell line which normally differentiates into m...
Expression of Fas Antigen and Bcl-2 Protein in Liver Tissues of Patients with Chronic Hepatitis B
Fas antigen Bcl-2 protein chronic hepatitis B
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2009/6/29
The aim of this study was to evaluate the role of apoptosis in chronic hepatitis B, and correlate it with disease severity. We studied the expression of the Fas antigen (FasAg) and Bcl-2 protein in a ...
Quantification of The FLI1 Gene Expression By Real-Time Quantitative RT-PCR
Gene expression FLI1 PML-RARA Real Time RT-PCR
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2009/6/25
In this study, quantification levels were investigated to define alterations in the expression of the FLI1 gene on acute promyelocytic leukemia (APL), which is characterized by a reciprocal t(15,17) t...
PCR Analysis of HSV-Negative Erythema Multiforme for the Expression of Other Herpesviruses
Erythema multiforme Epstein-Barr virus cytomegalovirus human herpesvirus-6 human herpesvirus-7 polymerase chain reaction
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2009/6/25
Background: Herpes simplex virus (HSV) is the primary herpesvirus implicated to have a causal role in erythema multiforme (EM), both in cases with an antecedent herpetic infection and in idiopathic EM...
Expression of the Tumour Suppressor Gene p53 in Odontogenic Cysts
Odontogenic cysts p53 protein immunohistochemistry
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2009/6/24
The protein p53 seems to be related to the suppression of cell proliferation. Positive tissues appear to have a higher proliferative activity than negative tissues. Mutation of the p53 tumour suppres...
Expression Analysis of DEK, AF4 and FLI1 Genes in All-Trans-Retinoic Acid (ATRA) Treated Acute Promyelocytic Leukaemia t(15;17) Patients by Quantitative Real-Time PCR
DEK AF4 FLI1 Acute Promyelocytic Leukemia All-Trans-Retimic Acid
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2009/6/23
All-trans retinoic acid (ATRA) sensitivity of acute promyelocytic leukaemia (APL) cells is strictly dependent on the presence of t(15;17), but the molecular background of this sensitivity remains obsc...
Various Expression Patterns of α1 and α2 Genes in IgA Deficiency
gene expression IgA subclasses partial IgA deficiency selective IgA deficiency α1 gene deletion
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2010/11/16
Background: IgA deficiency (IgAD) is the most common immunodeficiency, however the pathogenesis in most cases of IgAD is unknown. There are 2 subclasses of IgA, IgA1 and IgA2, and its heavy chains are...