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Altered testosterone feedback in pubertal male rats raised on reduced caloric intake
diet feedback FSH gonadotropins LH male nutrition
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2009/2/23
A study was conducted to explore the hypothesis that reduced caloric intake increases the negative feedback efficacy of testosterone on gonadotropin secretion. Daily subcutaneous injections of testost...
Reproductive aging in the Brown Norway rat is characterized by accelerated germ cell apoptosis and is not altered by luteinizing hormone replacement
Brown Norway rat accelerated germ cell apoptosis luteinizing hormone replacement
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2009/2/18
Reproductive aging in the male Brown Norway (BN) rat is characterized by decreased Leydig cell steroidogenesis associated with seminiferous tubule dysfunction. This could be a result of a combination ...
Altered basement membrane synthesis in the testis after tissue injury
Efferent duct ligation gene expression protein synthesis
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2009/2/17
The basement membrane plays an important role in maintaining the structural and functional integrity of tissues. Altered basement membrane structure has been associated with severe functional impair...
The duration of the cycle of the seminiferous epithelium is altered by administration of 2,5-hexanedione in the adult Sprague-Dawley rat
seminiferous epithelium 2,5-hexanedione adult Sprague-Dawley rat
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2009/2/13
The duration of the cycle of the seminiferous epithelium is believed to be under genetic control rather than being influenced by other factors. However, the frequencies of certain spermatogenic stag...
GnRH-A induced arrest of spermiogenesis in rats is associated with altered androgen binding protein distribution in the testis and epididymis
GnRH-antagonist Sertoli cell spermatogenesis
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2009/2/10
This study examines the effects of a potent gonadotropin releasing hormone (GnRH)-antagonist (GnRH-A, Ac-D[2] Nal1, 4-CL-D Phe2, D-Trp3, D-Arg6, D-Ala10) upon the distribution of androgen binding pr...
Altered testicular hormone production in infertile patients with idiopathic oligoasthenospermia
Testicular steroids human chorionic gonadotropin
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2009/2/7
We studied the kinetics of testicular response to human chorionic gonadotropin (hCG) in oligoasthenospermic and asthenospermic patients (OAZ-AZ). The responses of testosterone (T), androstenedione (...
Altered protamine 2 expression is uncommon in donors of known fertility, but common among men with poor fertilizing capacity, and may reflect other abnormalities of spermiogenesis
Semen sperm chromatin fertilization IVF infertility
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2008/12/29
During the spermatid elongation stage of spermiogenesis approximately 85% of sperm nuclear histones are replaced by protamines. Protamines increase the packing ratio of sperm chromatin, presumably fac...
Epididymal growth and differentiation are altered in human cryptorchidism
Epididymal growth differentiation human cryptorchidism
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2008/12/26
Despite the knowledge and histological classification of testicular lesions, epididymal lesions associated with cryptorchidism are not well defined and only macroscopic alterations have been reporte...
Mice Lacking Raf Kinase Inhibitor Protein-1 (RKIP-1) Have Altered Sperm Capacitation and Reduced Reproduction Rates With a Normal Response to Testicular Injury
PEBP testis
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2008/12/24
Raf kinase inhibitor protein-1 (RKIP-1) belongs to the phosphatidyl ethanolamine–binding family of proteins (PEBP), which are highly conserved throughout evolution and widely expressed in tissues...
Impaired Sperm Function After Spinal Cord Injury in the Rat Is Associated With Altered Cyclic Adenosine Monophosphate Signaling
cAMP SYBR-14 JC-1
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2008/12/23
Our previous observations of changes in the expression of cAMP-dependent genes and the cAMP-responsive element modulator (CREM) in rat testicular cells after spinal cord injury (SCI) implied abnor...