搜索结果: 16-29 共查到“知识库 生物学 STRUCTURAL”相关记录29条 . 查询时间(0.078 秒)
Structural Changes That Drive Timed Promoter Release In Transcription Reciprocally Lead To Abortive Instability
Biological sciences Aminopurine Abortive cycling Kinetics P266l Rna polymerase Transition Abortive instability
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2014/12/10
RNA polymerases carry out a process, which at times carries contradictory mechanistic requirements. During initiation, an RNA polymerase should be highly sequence specific, binding only to and initiat...
STRUCTURAL BIOLOGY AND PHARMACOLOGY OF HUMAN CATHEPSIN A AND NEURAMINIDASE 1
Cathepsin A Neuraminidase Lysosomal storage diseases sialidosis Galactosialidosis serine carboxypeptidase
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2014/12/10
Human cathepsin A (also known as Protective Protein/Cathepsin A, PPCA; E.C. 3.4.16.5) is a lysosomal serine carboxypeptidase. Cathepsin A is also involved in a complex with two other lysosomal enzymes...
Predicting effects of structural stress in a genome-reduced model bacterial metabolism
Predicting effects structural stress genome-reduced model bacterial metabolism
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2012/2/28
We studied in silico effects of structural stress in Mycoplasma pneumoniae, a genome-reduced model bacterial organism, by tracking the damage propagating on its metabolic network after a deleterious p...
Computational Studies of the Structural Stability of Rabbit Prion Protein Compared to Human and Mouse Prion Proteins
Neurodegenerative Diseases Prion Diseases Immunity Rabbit Prion Protein Rabbit NMR X-ray and Homology Structures
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2011/8/11
Abstract: Prion diseases are invariably fatal and highly infectious neurodegenerative diseases affecting humans and animals. The neurodegenerative diseases such as Creutzfeldt-Jakob disease, variant C...
New insight into kinetics behavor of the structural formation process in Agar gelation
kinetics behavor structural formation process Agar gelation
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2011/8/17
Abstract: A time-resolved experimental study on the kinetics and relaxation of the structural formation process in gelling Agar-water solutions was carried out using our custom-built torsion resonator...
Integrating temporal and spatial scales: Human structural network motifs across age and region-of-interest size
temporal spatial scales Human structural network motifs region-of-interest size age
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2011/8/5
Abstract: Human brain networks can be characterized at different temporal or spatial scales given by the age of the subject or the spatial resolution of the neuroimaging method. Integration of data ac...
Structural correlations and melting of B-DNA fibres
B-DNA fibres Structural correlations melting
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2011/9/13
Despite numerous attempts, the understanding of the thermal denaturation of DNA is still a challenge due to the lack of structural data at the transition since standard experimental approaches to DNA ...
Preliminary Functional-Structural Modeling on Poplar
Preliminary Functional-Structural Modeling Poplar
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2011/1/6
Poplar is one of the best fast-growing trees in the world, widely used for windbreak and wood product. Although architecture of poplar has direct impact on its applications, it has not been descried i...
Quantitative Genetics and Functional-Structural Plant Growth Models: Simulation of Quantitative Trait Loci Detection for Model Parameters and Application to Potential Yield Optimization
Quantitative Genetics Functional-Structural Plant Growth Models Simulation Quantitative Trait Loci Detection Model Parameters Application Potential Yield Optimization
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2010/11/16
Background and Aims: Prediction of phenotypic traits from new genotypes under untested environmental conditions is crucial to build simulations of breeding strategies to improve target traits. Althou...
Parametric identification of a functional-structural tree growth model and application to beech trees (Fagus sylvatica)
Parametric identification functional-structural tree growth model application to beech trees
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2010/11/16
Functional-structural models provide detailed representations of tree growth and their application to forestry seems full of prospects. However, owing to the complexity of tree architecture, parametr...
X-ray fiber diffraction modeling of structural changes of the thin filament upon activation of live vertebrate skeletal muscles
Thin filament Ca2+-regulation skeletal muscle X-ray fiber diffraction
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2010/12/2
In order to clarify the structural changes of the thin filaments related to the regulation mechanism in skeletal muscle contraction, the intensities of thin filament-based reflections in the X-ray fib...
Profile conditional random fields for modeling protein families with structural information
sequence analysis structure prediction fold recognition dynamic programming mean field approximation
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2010/12/2
A statistical model of protein families, called profile conditional random fields (CRFs), is proposed. This model may be regarded as an integration of the profile hidden Markov model (HMM) and the Fin...
群体遗传不平衡条件下的结构基因遗传共适应特性 Genetic Co-adaptability Among Structural Genes under the Condition of Genetic Disequilibrium
山羊群体 结构基因 遗传共适应 遗传不平衡
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2007/12/30
摘要本研究以柴达木山羊、柴达木绒山羊和辽宁绒山羊三个群体共147只山羊为材料，利用聚丙烯酰胺凝胶电泳（PAGE）技术检测了5种血液蛋白质（酶）基因座的遗传多态性，并进行了结构基因遗传共适应的研究，结果发现：45个基因座组合中有10个基因座组合处于遗传不平衡状态，并且这些遗传不平衡皆单纯由遗传共适应差异造成；除辽宁绒山羊Tf-PA-3组合的遗传不平衡包含非等位基因间的遗传共适应差异外，其他基因座组合...
Generation of a flexible loop structural ensemble and its application to induced-fit structural changes following ligand binding
docking simulation flexible loop modeling force-biased multicanonical molecular dynamics induced-fit structural ensemble
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2010/12/2
Molecular recognition is often mediated by flexible loops that have widely fluctuating structures and are sometimes disordered, but that form particular complex structures following ligand binding. In...