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Interplay between chaperones and protein disorder promotes the evolution of protein networks
Interplay between chaperones protein disorder promotes evolution protein networks
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2015/12/11
Evolution is driven by mutations, which lead to new protein functions but come at a cost to protein stability. Non-conservative substitutions are of interest in this regard because they may most profo...
Chemical interactions and configurational disorder in silicate melts
silicate melts structure entropy unmixing
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2015/9/10
The Thermodynamics of quasi-chemical and polymeric models are briefly reviewed. It is shown that the two
classes are mutually consistent, and that opportune conversion of the existing quasi-chemical ...
Construction of a Database of Secondary Structure Segments and Short Regions of Disorder and Analysis of Their Properties
Database Short Regions
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2015/5/27
Prediction of the secondary structure of a protein from its amino acid sequence
remains an important task. Not only did the growth of database holding only
protein sequences outpace that of solved p...
Conversation of Intrinsic Disorder in Protein Domains and Families
disorder protein domains
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2015/5/27
Protein regions which lack a fixed structure are called ‘disordered’. These intrinsically disordered regions are not only very common in many proteins, they are also crucial to the function of many pr...
Intrinsic Disorder in Transcription Factors
disorder transcription
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2015/5/26
Reported evidence suggested that high abundance of intrinsic disorder in eukaryotic genomes in comparison to bacteria and archaea may reflect the greater need for disorder-associated signaling and tra...
INTRINSIC DISORDER AND PROTEIN EVOLUTION:
Amino Acid Composition Protein Evolution Intrinsic Disorder
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2015/5/26
All twenty amino acids did not appear simultaneously in nature. Instead some of them appeared early, while others were added into the genetic code later. The amino acids that were formed by Miller (19...
Mechanisms of binding diversity in protein disorder : molecular recognition features mediating protein interaction networks
Many-to-one binding Partner selection MoRF
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2015/5/25
Intrinsically disordered proteins are proteins characterized by lack of stable tertiary structures under physiological conditions. Evidence shows that disordered proteins are not only highly involved ...
Conversation of Intrinsic Disorder in Protein Domains and Families
disorder protein domains
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2015/1/9
Protein regions which lack a fixed structure are called ‘disordered’. These intrinsically disordered regions are not only very common in many proteins, they are also crucial to the function of many pr...
Superfluid-Insulator Transition in a Commensurate One-Dimensional Bosonic System with Off-Diagonal Disorder
Quantum phase transition d lattice boson system monte carlo simulation of the superfluid
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2014/12/20
We study the nature of the superfluid-insulator quantum phase transition in a one-dimensional system of lattice bosons with off-diagonal disorder in the limit of a large integer filling factor. Monte ...
Superfluid Transition in a Bose Gas with Correlated Disorder
Three dimensional gas superfluid dielectric quantum monte carlo space simulation
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2014/12/19
The superfluid transition of a three-dimensional gas of hard-sphere bosons in a disordered medium is studied using quantum Monte Carlo methods. Simulations are performed in continuous space both in th...
Dilute Bose gas with correlated disorder: a path integral Monte Carlo study
Dilute bose gas thermodynamics integral monte carlo method the continuous space superfluids quantum
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2014/12/19
We investigate the thermodynamic properties of a dilute Bose gas in a correlated random potential using exact path integral Monte Carlo methods. The study is carried out in continuous space and disord...
《Obsessive–Compulsive Disorder And Its Spectrum: A Life-Span Approach》（图）
A Life-Span Approach Obsessive–Compulsive Disorder
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2013/12/6
Obsessive–compulsive spectrum disorders are conditions that, while not meeting diagnostic criteria for obsessive–compulsive disorder, share many similar symptoms. This book reviews the latest research...
Excitonic effects from geometric order and disorder explain broadband optical absorption in eumelanin
geometric order disorder explain broadband optical absorption melanin
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2014/9/24
Eumelanin is a ubiquitous biological pigment, and the origin of its broadband absorption spectrum has long been a topic of scientific debate. Here, we report a first-principles computational investiga...
Single Nucleotide Polymorphisms of NLRP12 Gene and Association with Non-specific Digestive Disorder in Rabbit
NLRP12 SNP Non-specific Digestive Disorder Case-control Study Rabbit
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2016/5/12
The NLRP12 (NLR family, pyrin domain containing 12) serves as a suppressor factor in the inflammatory response and protects the host against inflammation-induced damage. In the present study, we aimed...
Equilibrium-reduced density matrix formulation: Influence of noise, disorder, and temperature on localization in excitonic systems
Equilibrium-reduced density matrix formulation noise disorder temperature localization in exciton systems
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2014/9/24
An exact method to compute the entire equilibrium-reduced density matrix for systems characterized by a system-bath Hamiltonian is presented. The approach is based upon a stochastic unraveling of the ...