搜索结果: 1-3 共查到“知识库 APE/Ref-1”相关记录3条 . 查询时间(0.031 秒)
Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation
APE/Ref-1 reactive oxygen species redox
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2014/12/12
Reactive oxygen species (ROS) arise through normal cellular aerobic respiration, and, in combination with external sources such as ionizing radiation, cigarette tar and smoke, and particulate matter g...
Prognostic role of Ape/Ref-1 subcellular expression in stage I-III breast carcinomas
DNA repair breast carcinoma immunohistochemistry
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2014/12/12
The purpose of the study was to evaluate the prognostic role of the DNA repair protein APE/Ref-1 in breast carcinomas. Immunohistochemical analysis for APE/Ref-1 was performed in a series of 133 conse...
PC12细胞APE/ref-1cDNA的克隆和表达
PC12细胞 APEref1 RTPCR 克隆和表达
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2007/12/19
摘要 APE Ref 1是双功能核蛋白 ,它既能在碱基切除修复过程中切除脱嘌呤 脱嘌啶位点 ,又能促进包括AP 1、Myb和NF κB等受氧化还原调节的转录因子对DNA的结合 .从PC12细胞中抽提总RNA ,经逆转录PCR(RT PCR)扩增出APE ref 1cDNA并克隆到pQE3 1表达质粒上的BamHⅠ和PstⅠ位点间 .经测序表明 ,PC12细胞的APE ref 1cDNA以正确的阅...