搜索结果: 1-15 共查到“知识库 DNA Damage”相关记录25条 . 查询时间(0.718 秒)
SMC5/6 Complex Subunit NSE4A is Involved in DNA Damage Repair and Seed Development in Arabidopsis
Seed Development DNA Damage NSE4A subunit SMC5/6 Complex
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2024/3/4
The maintenance of genome integrity over cell divisions is critical for plant development and the correct transmission of genetic information to the progeny. A key factor involved in this process is t...
Spatially localized generation of nucleotide sequence-specific DNA damage
sperm chemotaxis fertilization TPX-1 AEG CRISP
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2016/5/23
Psoralens linked to triplex-forming oligonucleotides (psoTFOs) have been used in conjunction with laser-induced two-photon excitation (TPE) to damage a specific DNA target sequence. To demonstrate tha...
DNA damage of blood lymphocytes and neutrophils in cattle with lymphosarcoma
apoptosis cattle lymphocytes lymphosarcoma neutrophils
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2015/4/15
The objective of the present study was to analyze the apoptotic process in peripheral blood mononuclear cells (PBMC) and polymorphonuclear neutrophil leukocytes (PMN) in cows clinically affected with ...
The Role Of ERα, ERβ And Phytoestrogens From Soy In P53- Mediated Response To Dna Damage In Mammary Epithelium
Biological sciences Breast cancer Estrogen receptors Mammary tumors p53 Phytoestrogens DNA damage
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2014/12/11
Estrogenic compounds can stimulate proliferation of the mammary epithelium, but also potentiate the activity of the p53 tumor suppressor protein. These contradictory activities of estrogenic compounds...
Calculation of complex DNA damage induced by ions
Calculation complex DNA damage ions
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2011/8/3
Abstract: This paper is devoted to the analysis of the complex damage of DNA irradiated by ions. The analysis and assessment of complex damage is important because cells in which it occurs are less li...
Level of DNA Damage in Lead-Exposed Workers
lead comet assay DNA damage occupational exposure
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2010/12/22
Lead plays a significant role in modern industry. This metal is related to a broad range of physiological, biochemical and behavioural dysfunctions. The genotoxic effects of lead have been studied bot...
IS CONCENTRATION AND MOTILITY OF MALE GAMETES RELATED TO DNA DAMAGE MEASURED BY COMET ASSAY?
spermatozoa DNA damage Comet assay quality of sperm
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2010/12/22
Approximately 8% of couples in the World have problem with offspring production.Male infertility, which is the reason of the half of reproduction failures, is connected with diminished sperm productio...
Study of DNA damage induced by dental bleaching agents in vitro
CHO cells Comet assay Tooth bleaching Mutagenicity tests
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2009/10/19
Dental bleaching is a simple and conservative procedure for aesthetic restoration of vital and non-vital discolored teeth. Nevertheless, a number of studies have demonstrated the risk of tissue damage...
A Preliminary Study of DNA Damage in Peripheral Lymphocytes from Lung Cancer Patients and Healthy Subjects
Comet assay DNA damage Lung cancer Lymphocyte
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2009/6/24
A pilot study was undertaken to investigate the differences in oxidative DNA damage and 2-h DNA repair in peripheral lymphocytes between lung cancer patients and healthy subjects. Twenty-four lung ca...
Protective Effects of Melanoidins Derived from Soy Sauce and Soy Paste on NO-Induced DNA Damage
melanoidin DNA damage comet assay
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2009/6/17
We determined the protective activity of melanoidins against DNA damage using the comet assay. We used nitric oxide (NO) as a DNA damaging agent and HL60 (human promyelocytic leukemic cell line). Mela...
Genetic Studies of Bone Diseases: Evidence for Involvement of DNA Damage Response Proteins in Bone Remodeling
p53 Atm c-Abl osterix osteoblast osteoporosis
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2009/4/20
Bone remodeling is carried out by bone marrow mesenchymal stem cell derived osteoblasts, which form the bones, and hematopoeitic stem cell derived osteoclasts, which absorb the bones. Their actions a...
Localization of oxidative DNA damage after Au injection and effects of Au on Cp in renal kidney
Gold (Au) Copper (Cu) Ceruloplasmin (Cp) 8-hydroxydeoxyguanosine (8-OHdG) Metallotionein (MT)
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2009/4/1
The present study was carried out to investigate the effect of gold (Au) injection on copper (Cu) and two types of ceruloplasmin (Cp), total Cp (ID1) and active Cp (ID2), metallothionein (MT) in the s...
Mechanisms of the DNA Damage in Rat Kidney after Au Injection
Gold (Au) Copper (Cu) 8-hydroxydeoxyguanosine (8-OHdG) DNA damage Metallothionein (MT)
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2009/3/16
Au (gold) is a heavy metal and its complexes are one of the more effective medicaments available for rheumatoid arthritis, although many authors have reported serious kidney damage during the chrysoth...
The Effects of Vitamin C on Oxidative DNA Damage and Mutagenesis
antigenotoxic potential S. cerevisiae reversion assay yeast comet assay
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2009/3/6
DNA damage induced by reactive oxygen species is involved in mutagenesis and generation of mutation-related diseases, including cancer. Therefore, study of antigenotoxic potential of antioxidants is o...
Evaluation of oxidative DNA damage in human sperm and its association with male infertility
8-Hydroxydeoxyguanosine spermatozoa infertility
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2009/2/18
Recently, there is increasing evidence suggesting that oxidative sperm DNA damage is closely associated with impaired sperm function and male infertility. 8-Hydroxydeoxyguanosine (8-OHdG) is consi...