搜索结果: 1-12 共查到“知识库 drug discovery”相关记录12条 . 查询时间(0.031 秒)
A novel tissue-engineered 3D tumor model for anti-cancer drug discovery
decellularized porcine lung matrix breast tumor model biocompatibility CARS drug resistance
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2023/3/1
Cancer biology and drug discovery are heavily dependent on conventional 2D cell culture systems. However, a 2D culture is significantly limited by its ability to reflect 'true biology' of tumor in viv...
Bioinformatics and Pharmacogenomics in Drug Discovery and Development
Bioinformatics Pharmacogenomics
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2015/5/27
Objective: Literature review to evaluate the extent to which Bioinformatics has facilitated the drug discovery and development process from an economic perspective
Problem: A plethora of genomic and ...
Bioinformatics and Pharmacogenomics in Drug Discovery and Development- a Socio-economic Perspective
U.S Human Genome Project pharmacogenomics Socio-economic
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2015/5/26
A plethora of genomic and proteomic information was uncovered by the U.S Human Genome Project (HGP) – mostly by means of bioinformatics tools and techniques. Despite the impact that bioinformatics and...
System biology modeling : the insights for computational drug discovery
Drug Repositioning Machine Learning Side Effect
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2015/5/26
Traditional treatment strategy development for diseases involves the identification of target proteins related to disease states, and the interference of these proteins with drug molecules. Computatio...
Do Firms Change Capabilities by Hiring New People?A Study of the Adoption of Science-based Drug Discovery
Selection and Staffing Change Science Health Information
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2015/5/14
Do Firms Change Capabilities by Hiring New People?A Study of the Adoption of Science-based Drug Discovery.
Bioinformatics and Pharmacogenomics in Drug Discovery and Development- a Socio-economic Perspective
bioinformatics drug development U.S Human Genome Project pharmacogenomics Socio-economic
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2015/1/9
A plethora of genomic and proteomic information was uncovered by the U.S Human Genome Project (HGP) – mostly by means of bioinformatics tools and techniques. Despite the impact that bioinformatics and...
Simulated Drug Discovery Process to Conduct a Synoptic Assessment of Pharmacy Students
synoptic assessment drug discovery integrated learning simulation
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2018/7/3
Objective. To implement and assess a task-based learning exercise that prompts pharmacy students to integrate their understanding of different disciplines.
Design. Master of pharmacy (MPharm degree) ...
Ensembling Classification Models Based on Phalanxes of Variables with Applications in Drug Discovery
classification ranking ensemble random forest cluster pha-lanx
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2013/4/28
We have proposed an ensemble method which aggregates over clusters of predictor variables. We form the clusters (we call phalanxes) by joining variables together. The variables in a phalanx are good t...
Multi-level complexities in technological development: Competing strategies for drug discovery
applied science pharmaceuticals development methodology technology
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2009/4/29
Drug development regularly has to deal with complex circumstances on two levels: the local level of pharmacological intervention on specific target proteins, and the systems level of the effects of ph...
N-Linked Oligosaccharide Processing Enzymes as Molecular Targets for Drug Discovery
α-glucosidase ER glucosidase inhibitor anti-viral activity
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2008/4/20
N-Linked oligosaccharide processing enzymes are key enzymes in the biosynthesis of N-linked oligosaccharides. These enzymes are a molecular target for inhibition by anti-viral agents that interfere wi...
《Optimizing the Drug-Like Properties of Leads in Drug Discovery》（图）
Optimizing the Drug-Like Properties of Leads in Drug Discovery Ronald T. Borchardt Edward H. Kerns Michael Hageman Dhiren R. Thakker James L. Stevens
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2013/12/4
This title is the fourth volume of the AAPS series, Biotechnology: Pharmaceutical Aspects. Based on workshops organized by the American Association of Pharmaceutical Scientists in 2003 and 2004, Optim...
《Pharmaceutical Profiling in Drug Discovery for Lead Selection》（图）
Pharmaceutical Profiling in Drug Discovery for Lead Selection Ronald T. Borchardt Edward H. Kerns Christopher A. Lipinski Dhiren R. Thakker Binghe Wang
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2013/12/4
Volume 1 of the AAPS Press series, Biotechnology: Pharmaceutical Aspects. Based on a 2003 AAPS workshop of the same name, Pharmaceutical Profiling in Drug Discovery for Lead Selection emphasizes the i...