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输卵管作为精卵结合的必经之路,其微环境对精子在输卵管中的定向运动及后期的成功受精极为关键。临床发现,并非精力充沛、运动速度快的精子能够在众多竞争中胜出,而是埋伏在输卵管壁面绒毛内的精子,等待合适的时机才能迁移到卵子附近完成受精。然而,对精子与输卵管上皮细胞表面的相互作用,以及从静态到苏醒并迁移的过程,现有的实验方法和理论研究仍颇受挑战。
在细胞中,无论是胞内囊泡与细胞器还是胞外的分泌囊泡,大量膜蛋白可以在具有极高曲率的弯曲膜上 (曲率半径<50 nm)分布并维持其结构域,为了理解这些膜蛋白与高曲率膜的依存关系及其功能行为,人们亟需一种模型体系进行膜结构的仿生研究,而粒径大小精确可控的脂质体可以提供这样的理想平台(粒径与曲率成反比)。在现有的脂质体制备策略中,粒径大小的调控依赖于制备条件、均一化的处理方式及纯化方式等,但得到的脂质体...
阿尔兹海默症(Alzheimer disease,AD)是一种神经系统退行性疾病,以记忆障碍、失语、失用、失认、视空间技能损害等为主要症状。据世界卫生组织统计,截止2018年底,全球痴呆人数已经超过5000万人,其中AD患者约占70%,AD已成为影响全球的重大公共健康问题。
The Mirge-Naqshineh gold district is situated at northwest of Iran with a NW-trending brittle-ductile shear zone. It is hosted by Precambrian meta-sedimentary and meta-volcanic units traversed by mine...
The understanding of evolution of solar system has been recently entered a phase of major change with the results of new astronomical observation, several primitive extraterrestrial samples includi...
Stark spectroscopy has been applied to a wide range of molecular systems and materials. A generally useful method for obtaining electronic and vibrational Stark spectra that does not require sophistic...
Over the last few decades, quantum chemistry has progressed through the development of computational methods based on modern digital computers. However, these methods can hardly fulfill the exponentia...
Introduction to Quantum Algorithms for Physics and Chemistry     Introduction  Quantum Algorithms  Physics  Chemistry       font style='font-size:12px;'> 2016/1/22
Controllable quantum systems provide unique opportunities for solving problems in quantum chemistry and many-body physics that are intractable by classical computers. This approach is called “quantum ...
Popocatepetl volcano is a high-risk active volcano in Central Mexico where the highest population density in the country is settled. Radon in the soil and groundwater together with water chemistry fr...
A parameterization for secondary organic aerosol (SOA) production based on the volatility basis set (VBS) approach has been coupled with microphysics and radiative schemes in the Weather Research and ...
Water chemistry and soil radon survey at the Poas volcano (Costa Rica)     Poas volcano  geochemistry  radon  precursor       font style='font-size:12px;'> 2015/9/10
Radon-in-soil monitoring at the Poas volcano (Costa Rica) has been performed together with water chemistry from the hot crater lake since 1981 and 1983 respectively. The results are discussed as a fu...
Of recent, the rapid deterioration of groundwater quality in Port Harcourt, Southern Nigeria due to unregulated exploitation resulting from increasing growth in the oil and gas production activities h...
Direct monitoring of stream water chemistry is an increasingly important tool for securing stream water quality and assessing stream ecological functioning as it relates to overall ecosystem health. S...
Chemical processes in the ocean and at its interfaces with the atmosphere and the seafloor play a major role in regulating global biogeochemical cycles. Predicting the impact of human disturbances on ...
The convective transport module, CVTRANS, of the ECHAM/MESSy Atmospheric Chemistry (EMAC) model has been revised to better represent the physical flows and incorporate recent findings o...

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