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Inhibition of protein synthesis in Escherichia coli by expression of RNAs containing multiple ribosome binding sites
To get together the biosynthesis of chemical biological synthesis mRNA
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2014/12/11
Biologically synthesized poly(α,L-glutamic acid) (PLGA) can be chemically modified to form monodisperse poly(γ-benzyl α,L-glutamate) (PBLG). This material shows rare smectic ordering where macromolecu...
Understanding the allosteric mechanism of the Escherichia coli Hsp70 molecular chaperone, DnaK
Hsp70 Protein aggregation Enzyme Polypeptide Protein function Nucleotides. The ATP hydrolysis
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2014/12/11
The Hsp70 family molecular chaperones prevent protein aggregation under heat shock conditions. They are highly conserved, and have a N-terminal ATPase domain, which binds and hydrolyzes ATP, and a C-t...
Toward an understanding of the role of the L1 stalk in translocation by the Escherichia coli ribosome
Ribosomes the extension of cyclic code metastable state catalytic interactive translocation protein
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2014/12/11
Translocation is the process by which the ribosome advances the mRNA:tRNA complex by a one-codon step during the elongation cycle of translation. In the pre-translocation state, the ribosome transitio...
The Conformational Gymnastics of the Escherichia Coli SecA Molecular Machine and its Interactions with Signal Sequences
SecA Signal sequences Molecular machines
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2014/12/10
Protein secretion is a selective and regulated process that is essential in all organisms. In bacteria the preprotein translocase SecA, either free in the cytosol or associated with the SecYEG translo...
Toward an understanding of the role of the L1 stalk in translocation by the Escherichia coli ribosome
Biological sciences Hybrid state L1 Ribosome rRNA Translocation
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2014/12/10
Translocation is the process by which the ribosome advances the mRNA:tRNA complex by a one-codon step during the elongation cycle of translation. In the pretranslocation state, the ribosome transition...